ABHD6 Antibodies

AND ABHD6 ELISA kits, ABHD6 Proteins

Many biological assays use antibodies to detect ABHD6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABHD6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABHD6 antibodies...

We validate the specificity of these antibodies to ABHD6 by testing them on tissues known to express ABHD6 positively and negatively. Browse below to find the ABHD6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABHD6 Infographic by Boster Bio

All ABHD6 Products

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Product

Figures

Specificity

Applications

Price

ABHD6 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from COLO cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1009
1 kit, containing one 96-well plate and all necessary reagents

Anti-Monoacylglycerol lipase ABHD6 ABHD6 Antibody

Western Blot analysis of various cells using ABHD6 Polyclonal Antibody

Western blot analysis of lysates from COLO cells, using ABHD6 Antibody

Immunofluorescence analysis of A549 cells, using ABHD6 Antibody

Human, Mouse, Rat

ELISA, IF, WB

$380
Cat # A07754
100ul

ABHD6 (NM_020676) Human Over-expression Lysate

Human

$628
Cat # LS057406
20 µg, 100 µg

ABHD6 Overview

Facts about Monoacylglycerol lipase ABHD6.

ABHD6 3D structure. Source: alphafold

Monoacylglycerol lipase ABHD6 (ABHD6)

Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways.

May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). .

Gene Information

Human
Gene Name:	ABHD6
Uniprot:	Q9BV23
Entrez:	57406

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

2-arachidonoylglycerol hydrolase; abhydrolase domain containing 6; Abhydrolase domain-containing protein 6; EC 3.1.1.23; lipase protein; monoacylglycerol lipase ABHD6

Molecular Weight

Mass (kDA):
38.331 kDA

Genomic Context


Human

Location:	3p14.3
Sequence:	3; NC_000003.12 (58237502..58294736)

Subcellular Localizations

Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.

Diseases

Nervousness
Depressive Disorder
Neoplasms
Anxiety Disorders
Malignant Neoplasms
Intraocular Pressure Disorder
Neurodegenerative Disorders
Pain
Inflammation

Bone Neoplasms
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)

Pathways

Localization
Cell Migration
Cell Growth
Synaptic Transmission

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABHD6

References

PMID: 22969151 by Navia-Paldanius D., et al. Biochemical and pharmacological characterization of human alpha/beta- hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).

PMID: 26491015 by Pribasnig M.A., et al. alpha/beta hydrolase domain-containing 6 (ABHD6) degrades the late endosomal/lysosomal lipid bis(monoacylglycero)phosphate.