ACAT2 Antibodies

AND ACAT2 ELISA kits, ACAT2 Proteins

Many biological assays use antibodies to detect ACAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACAT2 antibodies...

We validate the specificity of these antibodies to ACAT2 by testing them on tissues known to express ACAT2 positively and negatively. Browse below to find the ACAT2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACAT2 Infographic by Boster Bio

All ACAT2 Products

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Anti-ACAT2 Antibody

Western blot analysis of extracts of various cell lines, using ACAT2 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded rat ovary using ACAT2 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon carcinoma using ACAT2 antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A03245
100ul

Human ACAT2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9BWD1
Starting from 20ug

Anti-ACAT2 Mouse Monoclonal Antibody [Clone ID: OTI5F7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACAT2 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ACAT2 monoclonal antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ACAT2 mouse monoclonal antibody

+10

Dog, Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M03245-1
100 µl

Anti-ACAT2 Mouse Monoclonal Antibody [Clone ID: OTI1B7]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M03245
100 µl

Anti-ACAT2 Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of ACAT2 using anti-ACAT2 antibody (M03245-2)

Human, Mouse, Rat

IHC, WB

$370
Cat # M03245-2
100 μl/vial

Anti-ACAT2 Antibody Picoband®

Western blot analysis of ACAT2 using anti-ACAT2 antibody (A03245-1)

Flow Cytometry analysis of HepG2 cells using anti-ACAT2 antibody (A03245-1)

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A03245-1
100 μg/vial

ACAT2 (NM_005891) Human Over-expression Lysate

Human

$628
Cat # LS000039
20 µg, 100 µg

ACAT2 Overview

Facts about Acetyl-CoA acetyltransferase, cytosolic.

ACAT2 3D structure. Source: alphafold

Acetyl-CoA acetyltransferase, cytosolic (ACAT2)

Gene Information

Human
Gene Name:	ACAT2
Uniprot:	Q9BWD1
Entrez:	39

Family

Belongs to:

thiolase-like superfamily

Alternative Names

acetoacetyl Coenzyme A thiolase; acetyl-CoA acetyltransferase 2; acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase); acetyl-Coenzyme A acetyltransferase 2; ACTL; Cytosolic acetoacetyl-CoA thiolase; EC 2.3.1; EC 2.3.1.9

Molecular Weight

Mass (kDA):
41.351 kDA

Genomic Context


Human

Location:	6q25.3
Sequence:	6; NC_000006.12 (159762045..159779112)

Subcellular Localizations

Cytoplasm, cytosol.

Diseases

Atherosclerosis
Hypercholesterolemia
Liver Carcinoma
Arteriosclerosis
Cardiovascular Diseases
Hyperlipidemia
Cholecystolithiasis
Coronary Heart Disease
Heart Diseases
Coronary Artery Disease
Obesity
Alzheimer's Disease

Dyslipidemias
Malignant Neoplasms
Fatty Liver
Liver Neoplasms
Liver Diseases
Insulin Resistance
Lecithin Acyltransferase Deficiency

Interacting Proteins

LNX1
TERF1

Pathways

Secretion
Cholesterol Esterification
Intestinal Cholesterol Absorption
Cholesterol Homeostasis
Transport
Localization
Excretion
Cholesterol Efflux
Cholesterol Transport
Methylation
Pathogenesis
Gallstone Formation
Glomerular Filtration

Cellular Localization
Chylomicron Assembly
Glycolysis
Hibernation
Aging
Gluconeogenesis
Oxidative Phosphorylation

PTMs

Methylation
Phosphorylation
Reduction

Oxidation
Glycosylation
Acylation

Research Areas

Cholesterol Metabolism
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACAT2

References

PMID: 7911016 by Song X.-Q., et al. Molecular cloning and nucleotide sequence of complementary DNA for human hepatic cytosolic acetoacetyl-coenzyme A thiolase.

PMID: 15733928 by Kursula P., et al. High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.