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- Table of Contents
Facts about Acyl-coenzyme A thioesterase 2, mitochondrial.
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Human | |
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Gene Name: | ACOT2 |
Uniprot: | P49753 |
Entrez: | 10965 |
Belongs to: |
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C/M/P thioester hydrolase family |
acyl-CoA thioesterase 2MTE1; Acyl-coenzyme A thioester hydrolase 2a; acyl-coenzyme A thioesterase 2, mitochondrial; CTE-Ia; EC 3.1.2.2; Long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; mitochondrial acyl-CoA thioesterase 2; peroxisomal long-chain acyl-coA thioesterase 2; PTE2A; PTE2CTE1A; ZAP128Mte1
Mass (kDA):
53.218 kDA
Human | |
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Location: | 14q24.3 |
Sequence: | 14; NC_000014.9 (73567620..73575658) |
Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.
Mitochondrion.
PMID: 7596406 by Sherrington R., et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
PMID: 16940157 by Hunt M.C., et al. Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.