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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase 6.
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Human | |
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Gene Name: | ACSL6 |
Uniprot: | Q9UKU0 |
Entrez: | 23305 |
Belongs to: |
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ATP-dependent AMP-binding enzyme family |
ACS2long-chain 6; acyl-CoA synthetase long-chain family member 6; EC 6.2.1; EC 6.2.1.3; FLJ16173; LACS 6; long fatty acyl-CoA synthetase 2; Long-chain acyl-CoA synthetase 6; long-chain-fatty-acid--CoA ligase 6
Mass (kDA):
77.752 kDA
Human | |
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Location: | 5q31.1 |
Sequence: | 5; NC_000005.10 (131949973..132012068, complement) |
Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
PMID: 10548543 by Malhotra K.T., et al. Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor.
PMID: 10502316 by Yagasaki F., et al. Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).