This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
ACSL6 Antibodies
AND ACSL6 ELISA kits, ACSL6 Proteins
Many biological assays use antibodies to detect ACSL6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACSL6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACSL6 antibodies...
Designing an IHC experiment for ACSL6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ACSL6 IHC GuideACSL6 Infographic by Boster Bio
All ACSL6 Products
Product
Figures
Specificity
Applications
Price
ACSL6 Overview
Facts about Long-chain-fatty-acid--CoA ligase 6.
Long-chain-fatty-acid--CoA ligase 6 (ACSL6)
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation through beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs generated may be used exclusively for the synthesis of the brain lipid.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ACSL6 |
| Uniprot: | Q9UKU0 |
| Entrez: | 23305 |
Family
| Belongs to: |
|---|
| ATP-dependent AMP-binding enzyme family |
Alternative Names
ACS2long-chain 6; acyl-CoA synthetase long-chain family member 6; EC 6.2.1; EC 6.2.1.3; FLJ16173; LACS 6; long fatty acyl-CoA synthetase 2; Long-chain acyl-CoA synthetase 6; long-chain-fatty-acid--CoA ligase 6
Molecular Weight
Mass (kDA):
77.752 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.1 |
| Sequence: | 5; NC_000005.10 (131949973..132012068, complement) |
Tissue Specificity
Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
Subcellular Localizations
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Diseases
- Schizophrenia
- Myeloid Leukemia
- Premature Menopause
- Refsum Disease
- Nervous System Disorder
- Ovarian Failure, Premature
- Tobacco Dependence Syndrome
- Infertility
- Oncogene Fusion
- Eosinophilic Leukemia
- Inhalation Exposure
- Fibrosis
Pathways
- Transport
- Cell Proliferation
- Pathogenesis
- Protein Palmitoylation
- Cell Migration
- Meiotic Prophase I
- Neuron Development
- Neuron Differentiation
- Oocyte Maturation
- Spermatogenesis
- Ribosome Biogenesis
- Translation
- Fatty Acid Transport
PTMs
- Phosphorylation
- Glycosylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACSL6
bosterbio.com/bosterbio-gene-info-cards/ACSL6
References
PMID: 10548543 by Malhotra K.T., et al. Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor.
PMID: 10502316 by Yagasaki F., et al. Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).