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- Table of Contents
Facts about Actin-related protein 3B.
May reduce the metastatic potential of tumors. .
Human | |
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Gene Name: | ACTR3B |
Uniprot: | Q9P1U1 |
Entrez: | 57180 |
Belongs to: |
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actin family |
actin-related protein 3B; actin-related protein 3-beta; actin-related protein Arp11; Actin-related protein ARP4; ARP11Actin-like protein 3B; ARP3 actin-related protein 3 homolog B (yeast); ARP3beta; ARP3-beta; ARP4; DKFZp686O24114
Mass (kDA):
47.608 kDA
Human | |
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Location: | 7q36.1-q36.2 |
Sequence: | 7; NC_000007.14 (152759749..153070979) |
Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential.
Cytoplasm, cytoskeleton. Cell projection.
PMID: 10806390 by Jay P., et al. ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells.
PMID: 11162478 by Shindo-Okada N., et al. Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma.