ADAM21 Antibodies

AND ADAM21 ELISA kits, ADAM21 Proteins

Many biological assays use antibodies to detect ADAM21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM21 antibodies...

We validate the specificity of these antibodies to ADAM21 by testing them on tissues known to express ADAM21 positively and negatively. Browse below to find the ADAM21 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADAM21 Infographic by Boster Bio

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ADAM21 Overview

Facts about Disintegrin and metalloproteinase domain-containing protein 21.

ADAM21 3D structure. Source: alphafold

Disintegrin and metalloproteinase domain-containing protein 21 (ADAM21)

May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients.

Gene Information

Human
Gene Name:	ADAM21
Uniprot:	Q9UKJ8
Entrez:	8747

Family

Belongs to:

No superfamily

Alternative Names

a disintegrin and metalloproteinase domain 21; ADAM 21; ADAM metallopeptidase domain 21; ADAM metallopeptidase domain 21, preproprotein; ADAM31; disintegrin and metalloproteinase domain-containing protein 21; EC 3.4.24.-; MGC125389

Molecular Weight

Mass (kDA):
80.834 kDA

Genomic Context


Human

Location:	14q24.2
Sequence:	14; NC_000014.9 (70452174..70459905)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Malignant Neoplasms
Leukemia
Adult T-cell Lymphoma/leukemia
Liver Carcinoma
Hepatitis
Leukemia, T-cell
Nervous System Disorder
Hepatitis B
Malignant Neoplasm Of Liver
Chromosome Inversion

Htlv-1 Infection
Carcinoma
Nervousness
Acute Promyelocytic Leukemia
Chromosomal Translocation

Pathways

Neurogenesis
Cell Adhesion
Transport
Cellular Response To Dsrna
Induction Of Apoptosis
Fertilization
Response To Dsrna
Intracellular Signal Transduction
Neuroblast Migration
Myelination
Erbb Signaling Pathway
T Cell Differentiation
Translation

System Development
Nervous System Development
Cell Differentiation
Dsrna Fragmentation
Catabolic Process
Ncrna Catabolic Process
Myoblast Fusion

PTMs

Disulfide bond

Glycoprotein

Zymogen

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM21

References

PMID: 10524237 by Poindexter K., et al. The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries.

PMID: 9469942 by Hooft van Huijsduijnen R.; ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha.