This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
ADAM28 Antibodies
AND ADAM28 ELISA kits, ADAM28 Proteins
Many biological assays use antibodies to detect ADAM28, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM28 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM28 antibodies...
Previous: SEPTIN9
Next: TSPAN9
ADAM28 Infographic by Boster Bio
All ADAM28 Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06873-2
100 μg/vial
Cat # A06873-2
100 μg/vial
ADAM28 Overview
Facts about Disintegrin and metalloproteinase domain-containing protein 28.
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM28)
May play a role in the adhesive and proteolytic events that happen during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ADAM28 |
| Uniprot: | Q9UKQ2 |
| Entrez: | 10863 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
a disintegrin and metalloproteinase domain 28; ADAM metallopeptidase domain 28; ADAM23MDC-L; ADAM28; disintegrin and metalloproteinase domain-containing protein 28; Dtgn1; EC 3.4.24; EC 3.4.24.-; eMDC II; eMDCII; Epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich proteinII; MDCL; MDCLADAM 28; MDC-Lm; MDC-Ls; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; Protein-L
Molecular Weight
Mass (kDA):
87.148 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p21.2 |
| Sequence: | 8; NC_000008.11 (24294040..24359014) |
Tissue Specificity
Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Tissue Adhesions
- Malignant Neoplasm Of Lung
- Metastatic Malignant Neoplasm To The Lymph Node
- Non-small Cell Lung Carcinoma
- Malignant Paraganglionic Neoplasm
- Inflammation
- Lung Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
Pathways
- Cell Proliferation
- Cell Adhesion
- Cell Cycle
- Localization
- Secretion
- Fertilization
- Proteolysis
- Neurogenesis
- Cell Migration
- Reverse Transcription
- Developmental Process
- Immune Response
- Virulence
PTMs
- Cleavage
Research Areas
- Cancer
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM28
bosterbio.com/bosterbio-gene-info-cards/ADAM28
References
PMID: 10506182 by Roberts C.M., et al. MDC-L, a novel metalloprotease disintegrin cysteine-rich protein family member expressed by human lymphocytes.
PMID: 10587367 by Jury J.A., et al. Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis.