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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 3.
.
| Human | |
|---|---|
| Gene Name: | ADAMTS3 |
| Uniprot: | O15072 |
| Entrez: | 9508 |

| Belongs to: |
|---|
| No superfamily |

A disintegrin and metalloproteinase with thrombospondin motifs 3; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 3; ADAM metallopeptidase with thrombospondin type 1 motif, 3; ADAM-TS 3; ADAMTS3; ADAM-TS3; ADAMTS-3; ADAMTS-4; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.14; KIAA0366PC II-NP; PC II-NP; Procollagen II amino propeptide-processing enzyme; Procollagen II N-proteinase; zinc metalloendopeptidase
Mass (kDA):
135.603 kDA

| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (72280969..72569221, complement) |
Found in cartilage and skin.
Secreted. Secreted, extracellular space, extracellular matrix.




PMID: 11408482 by Fernandes R.J., et al. Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis.
PMID: 28985353 by Brouillard P., et al. Loss of ADAMTS3 activity causes Hennekam lymphangiectasia-lymphedema syndrome 3.