ADARB2 Antibodies

AND ADARB2 ELISA kits, ADARB2 Proteins

Many biological assays use antibodies to detect ADARB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADARB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADARB2 antibodies...

We validate the specificity of these antibodies to ADARB2 by testing them on tissues known to express ADARB2 positively and negatively. Browse below to find the ADARB2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADARB2 Infographic by Boster Bio

All ADARB2 Products

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RED2 (ADARB2) (NM_018702) Human Over-expression Lysate

Human

$960
Cat # LS000105
20 µg, 100 µg

ADARB2 Overview

Facts about Double-stranded RNA-specific editase B2.

ADARB2 3D structure. Source: alphafold

Double-stranded RNA-specific editase B2 (ADARB2)

Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and reduces the efficiency of these enzymes.

Capable of binding to dsRNA but also to ssRNA. .

Gene Information

Human
Gene Name:	ADARB2
Uniprot:	Q9NS39
Entrez:	105

Family

Belongs to:

No superfamily

Alternative Names

ADAR3adenosine deaminase, RNA-specific, B2 (RED1 homolog rat); adenosine deaminase, RNA-specific, B2 (RED2 homolog rat); adenosine deaminase, RNA-specific, B2; double-stranded RNA-specific editase B2; dsRNA adenosine deaminase B2; EC 3.5; EC 3.5.1.2; EC 3.5.4; FLJ25034; homolog of rat BLUE; hRED2; RED2 homolog; RED2FLJ36975; RNA-dependent adenosine deaminase 3; RNA-editing deaminase 2; RNA-editing enzyme 2

Molecular Weight

Mass (kDA):
80.621 kDA

Genomic Context


Human

Location:	10p15.3
Sequence:	10; NC_000010.11 (1177313..1737525, complement)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Glioblastoma
Dyslipidemias
Glioma
Cardiovascular Diseases
Malignant Childhood Neoplasm
Hepatitis D Infection
Chimera Disorder
L1 Acute Lymphoblastic Leukemia
Glioblastoma Multiforme
Obesity, Abdominal

Hepatitis
Nervous System Disorder
Acute Lymphocytic Leukemia
Atherosclerosis
Diabetes Mellitus
Brain Neoplasms
Epilepsy

Pathways

Pathogenesis
Aging
Localization
Rna Interference
Oncogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADARB2

References

PMID: 10836796 by Chen C.-X., et al. A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.

PMID: 18178553 by Cenci C., et al. Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation.