- Table of Content
May regulate fluid exchange within epididymis. .
|G-protein coupled receptor 2 family|
|Sequence:||X; NC_000023.11 (18989307..19122956, complement)|
Epididymis-specific expression (at protein level). Both subunits are associated with apical membranes of efferent ductule and proximal epididymal duct epithelia. Mainly expressed in the nonciliated principal cells of the proximal excurrent ducts. Specifically over-expressed in Ewing sarcomas but also up-regulated in a number of carcinomas derived from prostate, kidney or lung.
Apical cell membrane; Multi-pass membrane protein.