ADRB1 Antibodies

AND ADRB1 ELISA kits, ADRB1 Proteins

Many biological assays use antibodies to detect ADRB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADRB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADRB1 antibodies...

We validate the specificity of these antibodies to ADRB1 by testing them on tissues known to express ADRB1 positively and negatively. Browse below to find the ADRB1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for ADRB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ADRB1 Western Blot Guide

ADRB1 Infographic by Boster Bio

All ADRB1 Products

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Anti-ADRB1 Antibody Picoband®

Western blot analysis of ADRB1 using anti-ADRB1 antibody (A00675-2)

Mouse, Rat

$370
Cat # A00675-2
100 μg/vial

ADRB1 Overview

Facts about Beta-1 adrenergic receptor.

ADRB1 3D structure. Source: alphafold

Beta-1 adrenergic receptor (ADRB1)

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.

Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. .

Gene Information

Human
Gene Name:	ADRB1
Uniprot:	P08588
Entrez:	153

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

ADRB1; ADRB1R; ADRB1RRHR; adrenergic, beta-1-, receptor; B1AR; beta-1 Adrenergic R; beta-1 adrenergic receptor; beta1 AdrenergicR; beta-1 AdrenergicR; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR

Molecular Weight

Mass (kDA):
51.323 kDA

Genomic Context


Human

Location:	10q25.3
Sequence:	10; NC_000010.11 (114043866..114046904)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.

Diseases

Hypertensive Disease
Heart Failure
Cardiovascular Diseases
Obesity
Myocardial Infarction
Dysequilibrium Syndrome
Diabetes Mellitus
Heart Diseases
Nervousness
Essential Hypertension
Infarction
Cardiac Failure Chronic
Cardiac Arrhythmia

Ischemia
Cerebrovascular Accident
Cardiomyopathies
Cholangiocarcinoma
Myocardial Ischemia
Insulin Resistance
Coronary Heart Disease

Interacting Proteins

ADORA1
Dlg4
DRD4
MAGI2
MAGI3

Pde4d

Pathways

Pathogenesis
Aging
Cell Death
Glomerular Filtration
Secretion
Transport
Response To Stress
Oxygen Homeostasis
Transmembrane Transport
Programmed Cell Death
Insulin Secretion
Proteolysis
Immune Response

Dna Methylation
Pigmentation
Response To Drug
Energy Homeostasis
Localization
Methylation
Membrane Depolarization

PTMs

Phosphorylation

Methylation

Research Areas

GPCR
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADRB1

References

PMID: 2825170 by Frielle T., et al. Cloning of the cDNA for the human beta 1-adrenergic receptor.

PMID: 10477438 by Moore J.D., et al. Racial differences in the frequencies of cardiac beta(1)-adrenergic receptor polymorphisms: analysis of c145A>G and c1165G>C.