AFG1-like ATPase (Afg1l)

Putative mitochondrial ATPase.

Plays a role in mitochondrial morphology and mitochondrial protein metabolism.

Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and regular activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.