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- Table of Contents

Facts about AFG3-like protein 1.
Putative ATP-dependent protease.
Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form..
| Mouse | |
|---|---|
| Gene Name: | Afg3l1 |
| Uniprot: | Q920A7 |
| Entrez: | 114896 |

| Belongs to: |
|---|
| No superfamily |

AFG3-like protein 1
Mass (kDA):
87.047 kDA

| Mouse | |
|---|---|
| Location: | 8|8 E1 |
| Sequence: | 8; |

PMID: 11549317 by Kremmidiotis G., et al. Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein.
PMID: 19656850 by Koppen M., et al. Autocatalytic processing of m-AAA protease subunits in mitochondria.