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- Table of Contents

Facts about Cytosolic carboxypeptidase 3.
Also removes gene-encoded polyglutamates or polyaspartates in the carboxy-terminus of target proteins like MYLK. Doesn't show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin.
| Mouse | |
|---|---|
| Gene Name: | Agbl3 |
| Uniprot: | Q8CDP0 |
| Entrez: | 76223 |

| Belongs to: |
|---|
| peptidase M14 family |

Cytosolic carboxypeptidase 3
Mass (kDA):
116.378 kDA

| Mouse | |
|---|---|
| Location: | 6|6 B1 |
| Sequence: | 6; |
Widely expressed. Expressed abundantly in tissues with m otile cilia such as testis, lung and trachea. Abundantly expressed in pituitary and kidney, moderately expressed in brain, eye, fat, pancreas, stomach, and adrenal.

PMID: 17244818 by Kalinina E., et al. A novel subfamily of mouse cytosolic carboxypeptidases.
PMID: 25103237 by Tort O., et al. The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.