Akirin-2 Antibodies

AND AKIRIN2 ELISA kits, Akirin-2 Proteins

Many biological assays use antibodies to detect Akirin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Akirin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Akirin-2 antibodies...

We validate the specificity of these antibodies to Akirin-2 by testing them on tissues known to express AKIRIN2 positively and negatively. Browse below to find the AKIRIN2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AKIRIN2 Infographic by Boster Bio

All AKIRIN2 Products

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Anti-Akirin-2 Akirin2 Antibody

Western blot analysis of Akirin2 in mouse brain tissue lysate with Akirin2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Human, Mouse

ELISA, WB

$481
Cat # A08948
0.1 mg

Anti-Akirin-2 Akirin2 Antibody

Western blot analysis of Akirin2 in Human Brain tissue lysate with Akirin2 antibody at 0

Human, Mouse, Rat

ELISA, WB

$481
Cat # A08948-1
0.1 mg

AKIRIN2 (NM_018064) Human Over-expression Lysate

Human

$628
Cat # LS055122
20 µg, 100 µg

AKIRIN2 Overview

Facts about Akirin-2.

AKIRIN2 3D structure. Source: alphafold

Akirin-2 (AKIRIN2)

Required for the innate immune reaction. Downstream effector of this Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways resulting in the production of IL-6.

Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity). .

Gene Information

Human
Gene Name:	AKIRIN2
Uniprot:	Q53H80
Entrez:	55122

Family

Belongs to:

akirin family

Alternative Names

akirin 2; akirin-2; C6orf166; chromosome 6 open reading frame 166; dJ486L4.2; FBI1; FLJ10342; fourteen-three-three beta interactant 1

Molecular Weight

Mass (kDA):
22.496 kDA

Genomic Context


Human

Location:	6q15
Sequence:	6; NC_000006.12 (87674860..87702233, complement)

Tissue Specificity

Widely expressed with the highest expression in peripheral blood leukocytes.

Subcellular Localizations

Nucleus.

Diseases

Innate Immune Response
Carcinogenesis

Interacting Proteins

SPG21

Pathways

Innate Immune Response
Immune Response
Myoblast Proliferation

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKIRIN2

References

PMID: 18066067 by Goto A., et al. Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice.