AKR1B15 Antibodies

AND AKR1B15 ELISA kits, AKR1B15 Proteins

Many biological assays use antibodies to detect AKR1B15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR1B15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR1B15 antibodies...

We validate the specificity of these antibodies to AKR1B15 by testing them on tissues known to express AKR1B15 positively and negatively. Browse below to find the AKR1B15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AKR1B15 Infographic by Boster Bio

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AKR1B15 Overview

Facts about Aldo-keto reductase family 1 member B15.

AKR1B15 3D structure. Source: alphafold

Aldo-keto reductase family 1 member B15 (AKR1B15)

Isoform 1: Mainly functions as a reductive enzyme that catalyzes the reduction of androgens and estrogens with high positional selectivity (shows 17-beta-hydroxysteroid dehydrogenase activity) as well as 3-keto-acyl-CoAs. Has a strong selectivity towards NADP(H) (PubMed:25577493).

Gene Information

Human
Gene Name:	AKR1B15
Uniprot:	C9JRZ8
Entrez:	441282

Family

Belongs to:

aldo/keto reductase family

Alternative Names

Aldo-keto reductase family 1 member B15

Molecular Weight

Mass (kDA):
36.537 kDA

Genomic Context


Human

Location:	7q33
Sequence:	7; NC_000007.14 (134549110..134579869)

Tissue Specificity

Widely expressed. Expressed at highest levels in steroid-sensitive tissues, such as placenta, testis and adipose tissue.

Subcellular Localizations

[Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm, cytosol.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR1B15

References

PMID: 21276782 by Salabei J.K., et al. Functional expression of novel human and murine AKR1B genes.

PMID: 25577493 by Weber S., et al. Aldo-keto reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity towards steroids and 3-keto-acyl-coa conjugates.