Akr1c15 Antibodies

AND Akr1c15 ELISA kits, Akr1c15 Proteins

Many biological assays use antibodies to detect Akr1c15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Akr1c15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Akr1c15 antibodies...

We validate the specificity of these antibodies to Akr1c15 by testing them on tissues known to express Akr1c15 positively and negatively. Browse below to find the Akr1c15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Akr1c15 Infographic by Boster Bio

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Akr1c15 Overview

Facts about Aldo-keto reductase family 1 member C15.

Akr1c15 3D structure. Source: alphafold

Aldo-keto reductase family 1 member C15 (Akr1c15)

Catalyzes the NADPH-dependent reduction of many different substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids (PubMed:17574202). Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta- hydroxysteroids (PubMed:17574202).

To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols (PubMed:17574202). In the stomach, lung and colon tissues, mediates the decrease in farnesal and geranylgeranial to farnesol and geranylgeraniol respectively (PubMed:21187079).

Gene Information

Rat
Gene Name:	Akr1c15
Uniprot:	D3ZF77
Entrez:	361267

Family

Belongs to:

aldo/keto reductase family

Alternative Names

Aldo-keto reductase family 1 member C15

Molecular Weight

Mass (kDA):
37.195 kDA

Genomic Context


Rat

Location:	17q12.2
Sequence:	17;

Tissue Specificity

Expressed in lung, specifically in bronchiolar Clara cells, type II alveolar cells and epithelial cells of the duct of the bronchial gland (at protein level) (PubMed:17574202, PubMed:7511002, PubMed:21187079). Expressed in gastric parietal cells and in epithelial cells of the large intestine and colon (at protein level) (PubMed:17574202, PubMed:21187079). Expressed in brown adipocytes (at protein level) (PubMed:17574202). Expressed in vascular endothelial cells (at protein level) (PubMed:17574202).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Akr1c15

References

PMID: 7511002 by Qin K.N., et al. Structure and tissue-specific expression of the aldo-keto reductase superfamily.

PMID: 17574202 by Endo S., et al. Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues.