ALDH18A1 Antibodies

AND ALDH18A1 ELISA kits, ALDH18A1 Proteins

Many biological assays use antibodies to detect ALDH18A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALDH18A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALDH18A1 antibodies...

We validate the specificity of these antibodies to ALDH18A1 by testing them on tissues known to express ALDH18A1 positively and negatively. Browse below to find the ALDH18A1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ALDH18A1 Infographic by Boster Bio

All ALDH18A1 Products

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Anti-P5CS/ALDH18A1 Antibody Picoband®

1 Q&As

Western blot analysis of ALDH18A1 using anti-ALDH18A1 antibody (A06119-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A06119-2
100 μg/vial

P5CS (ALDH18A1) (NM_002860) Human Recombinant Protein

Coomassie blue staining of purified ALDH18A1 protein

$1062
Cat # PROTP54886
20 µg

P5CS (ALDH18A1) (NM_002860) Human Over-expression Lysate

Human

$628
Cat # LS005832
20 µg, 100 µg

Anti-Zebrafish P5CS/ALDH18A1 Antibody

IHC analysis of P5CS/ALDH18A1 using anti-P5CS/ALDH18A1 antibody (AZA4IGC8)

Zebrafish

IHC

$470
Cat # AZA4IGC8
100 μg/vial

ALDH18A1 Overview

Facts about Delta-1-pyrroline-5-carboxylate synthase.

ALDH18A1 3D structure. Source: alphafold

Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)

Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. .

Gene Information

Human
Gene Name:	ALDH18A1
Uniprot:	P54886
Entrez:	5832

Family

Belongs to:

No superfamily

Alternative Names

aldehyde dehydrogenase 18 family, member A1; Aldehyde dehydrogenase family 18 member A1; delta-1-pyrroline-5-carboxylate synthase; EC 2.1.2.11; EC 2.3.3.13; GSASdelta1-pyrroline-5-carboxlate synthetase; MGC117316; P5CSdelta-1-pyrroline-5-carboxylate synthetase; PYCSEC 1.2.1.41; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Molecular Weight

Mass (kDA):
87.302 kDA

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (95605938..95656901, complement)

Subcellular Localizations

Mitochondrion inner membrane.

Diseases

Developmental Delay (disorder)
Cutis Laxa
Neurocutaneous Syndromes
Joint Laxity
De Barsy Syndrome
Nerve Degeneration
Dementia
Down Syndrome
Connective Tissue Diseases
Muscle Hypotonia
Corneal Diseases

Dislocations
Nervousness
Alzheimer's Disease
Choreoathetosis
Geroderma Osteodysplastica

Interacting Proteins

AGTRAP
CMTM5

Pathways

Cell Proliferation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALDH18A1

References

PMID: 8761662 by Aral B., et al. Database cloning human delta 1-pyrroline-5-carboxylate synthetase (P5CS) cDNA: a bifunctional enzyme catalyzing the first 2 steps in proline biosynthesis.

PMID: 10037775 by Hu C.A., et al. Molecular enzymology of mammalian delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition.