ANKS1B Antibodies

AND ANKS1B ELISA kits, ANKS1B Proteins

Many biological assays use antibodies to detect ANKS1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANKS1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANKS1B antibodies...

We validate the specificity of these antibodies to ANKS1B by testing them on tissues known to express ANKS1B positively and negatively. Browse below to find the ANKS1B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANKS1B Infographic by Boster Bio

All ANKS1B Products

Product

Figures

Specificity

Applications

Price

Anti-ANKS1B Antibody

Human, Mouse, Rat

$405
Cat # A07165
100ul

ANKS1B (NM_152788) Human Over-expression Lysate

Human

$960
Cat # LS056899
100 µg

ANKS1B Overview

Facts about Ankyrin repeat and sterile alpha motif domain-containing protein 1B.

ANKS1B 3D structure. Source: alphafold

Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B)

Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. .

Gene Information

Human
Gene Name:	ANKS1B
Uniprot:	Q7Z6G8
Entrez:	56899

Family

Belongs to:

No superfamily

Alternative Names

Ankyrin repeat and sterile alpha motif domain-containing protein 1B

Molecular Weight

Mass (kDA):
138.066 kDA

Genomic Context


Human

Location:	12q23.1
Sequence:	12; NC_000012.12 (98729904..99984773, complement)

Tissue Specificity

Highly expressed in marrow from patients with pre-B ALL associated with the t(1;19) translocation. Strongly expressed in brain and testis. Expressed in fetal brain. Isoform 4 is highly expressed in brain (at protein level). Isoform 6 is expressed in brain and several cancer cell lines.

Subcellular Localizations

Cytoplasm.; [Isoform 2]: Nucleus.; [Isoform 3]: Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Nucleus. Nucleus, Cajal body. The synaptic localization requires DLG4 interaction. Translocation to the nucleus in response to stimulation of NMDA receptors (NMDARs) in a calcium-independent manner (By similarity).; [Isoform 4]: Nucleus. The interaction with APP causes its partial exclusion from the nucleus, when APP is overexpressed.; [Isoform 6]: Nucleus.

Interacting Proteins

COIL

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANKS1B

References

PMID: 15004329 by Ghersi E., et al. The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing.

PMID: 15862129 by Xu H., et al. A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.