Aldehyde oxidase 3 (Aox3)

Oxidase with wide substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and phthalazine, in addition to aldehydes, such as benzaldehyde, retinal and pyridoxal. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents.

Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of nitric oxide.