Apoptosis inhibitor 5 Antibodies

AND API5 ELISA kits, Apoptosis inhibitor 5 Proteins

Many biological assays use antibodies to detect Apoptosis inhibitor 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apoptosis inhibitor 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apoptosis inhibitor 5 antibodies...

We validate the specificity of these antibodies to Apoptosis inhibitor 5 by testing them on tissues known to express API5 positively and negatively. Browse below to find the API5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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API5 Infographic by Boster Bio

All API5 Products

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Anti-Apoptosis inhibitor 5/API5 Antibody Picoband®

6 Q&As

Western blot analysis of API5 using anti-API5 antibody (PA1009)

IHC analysis of API5 using anti-API5 antibody (PA1009)

ICC analysis of API5 using anti-API5 antibody (PA1009)

Human, Mouse, Rat

IF, IHC, IHC-F, ICC, WB

$370
Cat # PA1009
100 μg/vial

Anti-Apoptosis inhibitor 5 API5 Antibody

Western blotting validation for Anti-Apoptosis inhibitor 5 API5 Antibody A04637

Electrophoresis was performed on a SDS-PAGE gel

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A04637
100ul

Apoptosis inhibitor 5 (API5) (NM_001142931) Human Recombinant Protein

Coomassie blue staining of purified API5 protein

$1249
Cat # PROTQ9BZZ5
20 µg

API5 Overview

Facts about Apoptosis inhibitor 5.

API5 3D structure. Source: alphafold

Apoptosis inhibitor 5 (API5)

Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1.

By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to effectively suppress E2F1-induced apoptosis.

Gene Information

Human
Gene Name:	API5
Uniprot:	Q9BZZ5
Entrez:	8539

Family

Belongs to:

API5 family

Alternative Names

AAC-11API5L1; AAC11fibroblast growth factor 2-interacting factor 2; Antiapoptosis clone 11 protein; API-5; apoptosis inhibitor 5; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; FIF; migration-inducing protein MIG8; Protein XAGL

Molecular Weight

Mass (kDA):
59.005 kDA

Genomic Context


Human

Location:	11p12
Sequence:	11; NC_000011.10 (43311970..43344530)

Tissue Specificity

Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.

Subcellular Localizations

Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic.; [Isoform 3]: Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Liver Carcinoma
Cell Transformation, Neoplastic
Leukemia
Neoplasm Metastasis
Myeloid Leukemia, Chronic
Neoplasm Invasiveness
Non-small Cell Lung Carcinoma
Malignant Paraganglionic Neoplasm
Inflammation
Liver Neoplasms

Malignant Neoplasm Of Lung
Carcinogenesis
Cell Invasion
Lung Neoplasms
Drug-induced Liver Injury
Metastatic Malignant Neoplasm To The Lymph Node
Melanoma

Pathways

Cell Death
Programmed Cell Death
Lactation
Immune Response
Reverse Transcription
Parturition
Localization
Inflammatory Response
Sensitization

Cell Cycle
Cell Growth
Regulation Of Immune Response
Pathogenesis

PTMs

Phosphorylation

Cleavage

Acetylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/API5

References

PMID: 9307294 by Tewari M., et al. AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal.

PMID: 10393420 by Gianfrancesco F., et al. Molecular cloning and fine mapping of API5L1, a novel human gene strongly related to an antiapoptotic gene.