APOBEC1 Antibodies

AND APOBEC1 ELISA kits, APOBEC1 Proteins

Many biological assays use antibodies to detect APOBEC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with APOBEC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop APOBEC1 antibodies...

We validate the specificity of these antibodies to APOBEC1 by testing them on tissues known to express APOBEC1 positively and negatively. Browse below to find the APOBEC1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APOBEC1 Infographic by Boster Bio

All APOBEC1 Products

Product

Figures

Specificity

Applications

Price

APOBEC1 (NM_001644) Human Over-expression Lysate

Human

$628
Cat # LS000339
100 µg

APOBEC1 Overview

Facts about C->U-editing enzyme APOBEC-1.

APOBEC1 3D structure. Source: alphafold

C->U-editing enzyme APOBEC-1 (APOBEC1)

Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA.

May also play a role in the epigenetic regulation of gene expression by engaging in DNA demethylation. .

Gene Information

Human
Gene Name:	APOBEC1
Uniprot:	P41238
Entrez:	339

Family

Belongs to:

cytidine and deoxycytidylate deaminase family

Alternative Names

APOBEC-1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1; Apolipoprotein B mRNA-editing enzyme 1; BEDPC->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4; EC 3.5.4.-; HEPRapolipoprotein B mRNA editing enzyme complex-1

Molecular Weight

Mass (kDA):
28.192 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (7649400..7670599, complement)

Tissue Specificity

Expressed exclusively in the small intestine.

Subcellular Localizations

Cytoplasm.

Diseases

Hiv Infections
Immunologic Deficiency Syndromes
Neoplasms
Atherosclerosis
Malignant Neoplasms
Hepatitis B
Hepatitis
Leukemia
Retroviridae Infections
Hyperlipidemia
Hypercholesterolemia

Liver Carcinoma
Hypercholesterolemia, Familial
Infective Disorder
Dyslipidemias
Patient Dependence On
Virus Diseases

Pathways

Dna Deamination
Translation
Transport
Gene Conversion
Localization
Cytidine Deamination
Reverse Transcription
Lipid Transport
Demethylation
Secretion
Nuclear Export
Dna Repair
Methylation

Transposition
Immune Response
Pathogenesis
Viral Replication
Dna Demethylation
Platelet Activation
Spermatogenesis

PTMs

Deamination
Demethylation
Cleavage

Phosphorylation
Hydroxylation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOBEC1

References

PMID: 8208612 by Hadjiagapiou C., et al. Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.

PMID: 8078915 by Lau P.P., et al. Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.