ARHGAP22 Antibodies

AND ARHGAP22 ELISA kits, ARHGAP22 Proteins

Many biological assays use antibodies to detect ARHGAP22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGAP22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGAP22 antibodies...

We validate the specificity of these antibodies to ARHGAP22 by testing them on tissues known to express ARHGAP22 positively and negatively. Browse below to find the ARHGAP22 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGAP22 Infographic by Boster Bio

All ARHGAP22 Products

Product

Figures

Specificity

Applications

Price

Anti-Phospho-ARHGAP22 S397 Antibody

3 Q&As

Human, Mouse, Rat

$599
Cat # P10197
50ug

Anti-ARHGAP22 Antibody

Human

ELISA, IHC, WB

$380
Cat # A10197
100ul

ARHGAP22 (NM_021226) Human Over-expression Lysate

Human

$960
Cat # LS058504
100 µg

ARHGAP22 Overview

Facts about Rho GTPase-activating protein 22.

ARHGAP22 3D structure. Source: alphafold

Rho GTPase-activating protein 22 (ARHGAP22)

Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it into an inactive GDP-bound state.

Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating action of this endothelin-1 (EDN1) promoter (By similarity).

Gene Information

Human
Gene Name:	ARHGAP22
Uniprot:	Q7Z5H3
Entrez:	58504

Family

Belongs to:

No superfamily

Alternative Names

Rho GTPase activating protein 22; rho GTPase-activating protein 22; RhoGAP2; Rho-type GTPase-activating protein 22

Molecular Weight

Mass (kDA):
76.779 kDA

Genomic Context


Human

Location:	10q11.22-q11.23
Sequence:	10; NC_000010.11 (48429831..48656265, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear (By similarity).

Diseases

Neoplasms
Neoplasm Metastasis
Melanoma
Malignant Neoplasms
Carcinogenesis
Cell Invasion
Diabetic Retinopathy
Metastatic Melanoma
Malignant Neoplasm Of Kidney
Extravasation
Malignant Neoplasm Of Breast
Myeloproliferative Disease
Diabetes Mellitus

Neoplasm Invasiveness
Brain Neoplasms
Malignant Neoplasm Of Lung
Diabetes Mellitus, Non-insulin-dependent
Tumor Angiogenesis
Chondrosarcoma
Leukemia

Interacting Proteins

CACNA1A
CCNDBP1

Pathways

Cell Migration
Proteolysis
Regulation Of Cell Shape
Angiogenesis
Pathogenesis
Localization

PTMs

Phosphorylation

Research Areas

Diabetes Research
Lipid and Metabolism
Phospho-Specific

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGAP22

References

PMID: 15254788 by Katoh M., et al. Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico.