ARHGEF6 Antibodies

AND ARHGEF6 ELISA kits, ARHGEF6 Proteins

Many biological assays use antibodies to detect ARHGEF6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGEF6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGEF6 antibodies...

We validate the specificity of these antibodies to ARHGEF6 by testing them on tissues known to express ARHGEF6 positively and negatively. Browse below to find the ARHGEF6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGEF6 Infographic by Boster Bio

All ARHGEF6 Products

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Anti-ARHG6 ARHGEF6 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05317
100ul

Anti-ARHGEF6 Antibody Picoband®

Western blot analysis of ARHGEF6 using anti-ARHGEF6 antibody (A05317-1)

Flow Cytometry analysis of PC-3 cells using anti-ARHGEF6 antibody (A05317-1)

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A05317-1
100 μg/vial

ARHGEF6 Overview

Facts about Rho guanine nucleotide exchange factor 6.

ARHGEF6 3D structure. Source: alphafold

Rho guanine nucleotide exchange factor 6 (ARHGEF6)

Acts as a RAC1 guanine nucleotide exchange factor (GEF). .

Gene Information

Human
Gene Name:	ARHGEF6
Uniprot:	Q15052
Entrez:	9459

Family

Belongs to:

No superfamily

Alternative Names

alphaPIX; Alpha-Pix; COOL-2; COOL2alpha; KIAA0006Cool2; mental retardation, X-linked 46; MRX46; PAK-interacting exchange factor alpha; PIXA; Rac/Cdc42 guanine exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor 6; rho guanine nucleotide exchange factor 6

Molecular Weight

Mass (kDA):
87.499 kDA

Genomic Context


Human

Location:	Xq26.3
Sequence:	X; NC_000023.11 (136665547..136780945, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cell projection, lamellipodium.

Diseases

Fragile X Syndrome
Nervousness
Brain Neoplasms
Glioma
Anaplastic Astrocytoma
Carcinoma
Malocclusion
Sex Chromosome Disorders
Primary Central Nervous System Lymphoma
Malignant Neoplasms
Neoplasms

Dwarfism
Lymphoma
Epithelial Ovarian Cancer
Ovarian Neoplasm
Glioblastoma Multiforme

Interacting Proteins

NAA10
PAK2

Pathways

Pathogenesis
Methylation
Transport
Drug Resistance
Cytoskeleton Organization
Sensitization
Vesicle Transport
Translation
Induction Of Apoptosis

Cognition
Synaptic Vesicle Transport
Localization

PTMs

Methylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGEF6

References

PMID: 11017088 by Kutsche K., et al. Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation.

PMID: 11337747 by Lower K.M., et al. Characterization of ARHGEF6, a guanine nucleotide exchange factor for Rho GTPases and a candidate gene for X-linked mental retardation: mutation screening in Borjeson-Forssman-Lehmann syndrome and MRX27.