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- Table of Contents
ARID1A Antibodies
AND ARID1A ELISA kits, ARID1A Proteins
Many biological assays use antibodies to detect ARID1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARID1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARID1A antibodies...
Designing a Western blot for ARID1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ARID1A Western Blot GuideARID1A Infographic by Boster Bio
All ARID1A Products
Product
Figures
Specificity
Applications
Price
Anti-ARID1A Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00247-1
100 μl/vial
Cat # M00247-1
100 μl/vial
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00247-2
100 μg/vial
Cat # A00247-2
100 μg/vial
Human, Mouse, Rat
WB
$523
Cat # M00247
100 µl
Cat # M00247
100 µl
ARID1A Overview
Facts about AT-rich interactive domain-containing protein 1A.
AT-rich interactive domain-containing protein 1A (ARID1A)
Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by changing DNA-histone contacts within a nucleosome within an ATP-dependent method. Binds DNA non-specifically.
Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complicated ) as well as the neuron-specific chromatin remodeling complex (nBAF complicated ). During neural development a switch from a stem/progenitor into a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become dedicated to their adult state.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARID1A |
| Uniprot: | O14497 |
| Entrez: | 8289 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ARID domain-containing protein 1A; AT rich interactive domain 1A (SWI- like); AT rich interactive domain 1A (SWI-like); AT-rich interactive domain-containing protein 1A; B120SWI-like protein; BAF250a; BAF250SWI/SNF complex protein p270; BM029; brain protein 120; BRG1-associated factor 250; BRG1-associated factor 250a; C10rf4; C1orf4SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatinsubfamily F member 1; chromatin remodeling factor p250; hELD; hOSA1; matrix associated, actin dependent regulator of chromatin; Osa homolog 1; OSA1 nuclear protein; OSA1; P270; SMARCF1; subfam
Molecular Weight
Mass (kDA):
242.045 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.11 |
| Sequence: | 1; NC_000001.11 (26696015..26782104) |
Tissue Specificity
Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL, and at a much lower level in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Ovarian Neoplasm
- Adenocarcinoma, Clear Cell
- Endometriosis, Site Unspecified
- Carcinoma, Endometrioid
- Adenocarcinoma
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Ovary
- Malignant Paraganglionic Neoplasm
- Carcinogenesis
- Endometrial Polyp
Interacting Proteins
- HIC1
- SMARCA2
- SMARCA4
- TOP2A
Pathways
- Chromatin Remodeling
- Pathogenesis
- Cell Proliferation
- Cell Cycle
- Atp-dependent Chromatin Remodeling
- Chromatin Modification
- Methylation
- Cell Growth
- Cell Cycle Arrest
- Cell Differentiation
- Localization
- Rna Interference
- Cell Adhesion
PTMs
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARID1A
bosterbio.com/bosterbio-gene-info-cards/ARID1A
References
PMID: 11073988 by Nie Z., et al. A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex.
PMID: 12200431 by Inoue H., et al. Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.