cAMP-regulated phosphoprotein 19 (ARPP19)

Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, resulting in inactivation of PP2A, an important condition to maintain cyclin-B1-CDK1 activity high during M phase.

May indirectly enhance GAP-43 expression. .