Achaete-scute homolog 3 Antibodies

AND ASCL3 ELISA kits, Achaete-scute homolog 3 Proteins

Many biological assays use antibodies to detect Achaete-scute homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Achaete-scute homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Achaete-scute homolog 3 antibodies...

We validate the specificity of these antibodies to Achaete-scute homolog 3 by testing them on tissues known to express ASCL3 positively and negatively. Browse below to find the ASCL3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASCL3 Infographic by Boster Bio

All ASCL3 Products

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Achaete scute homolog 3 (ASCL3) (NM_020646) Human Recombinant Protein

Coomassie blue staining of purified ASCL3 protein

$1249
Cat # PROTQ9NQ33
20 µg

Anti-Achaete scute homolog 3 (ASCL3) Mouse Monoclonal Antibody [Clone ID: OTI1C5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ASCL3 (Right lane) cDNA for 48 hrs and lysed

Human

$523
Cat # M13709
100 µl

Achaete scute homolog 3 (ASCL3) (NM_020646) Human Over-expression Lysate

Human

$628
Cat # LS056676
20 µg, 100 µg

ASCL3 Overview

Facts about Achaete-scute homolog 3.

ASCL3 3D structure. Source: alphafold

Achaete-scute homolog 3 (ASCL3)

Transcriptional repressor. Inhibits myogenesis (By similarity).

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Gene Information

Human
Gene Name:	ASCL3
Uniprot:	Q9NQ33
Entrez:	56676

Family

Belongs to:

No superfamily

Alternative Names

achaete-scute complex homolog 3 (Drosophila); ASH-3; bHLH transcription factor Sgn-1 (Salivary Glands 1); bHLH transcriptional regulator Sgn-1; BHLHA42; bHLHa42achaete-scute homolog 3; Class A basic helix-loop-helix protein 42; hASH3; HASH3achaete-scute complex (Drosophila) homolog-like 3; Sgn1

Molecular Weight

Mass (kDA):
20.797 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (8937572..8943033, complement)

Tissue Specificity

Widely expressed in fetal and adult tissues.

Subcellular Localizations

Nucleus.

Diseases

Salivary Gland Diseases
Cytogenetic Abnormality
Placental Choriocarcinoma
Choriocarcinoma
Diphtheria

Pathways

Transport
Regeneration
Salivary Gland Development
Cell Proliferation
Fatty Acid Transport
Gland Development
Skin Development

Tissue Homeostasis
Cell Fate Specification

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASCL3

References

PMID: 11784080 by Yoshida S., et al. Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice.

PMID: 11528127 by Amid C., et al. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7.