ASXL3 Antibodies

AND ASXL3 ELISA kits, ASXL3 Proteins

Many biological assays use antibodies to detect ASXL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASXL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASXL3 antibodies...

We validate the specificity of these antibodies to ASXL3 by testing them on tissues known to express ASXL3 positively and negatively. Browse below to find the ASXL3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASXL3 Infographic by Boster Bio

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ASXL3 Overview

Facts about Putative Polycomb group protein ASXL3.

ASXL3 3D structure. Source: alphafold

Putative Polycomb group protein ASXL3 (ASXL3)

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to keep the transcriptionally repressive state of homeotic genes throughout development.

PcG proteins aren't required to initiate repression, but to keep it through later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity).

Gene Information

Human
Gene Name:	ASXL3
Uniprot:	Q9C0F0
Entrez:	80816

Family

Belongs to:

Asx family

Alternative Names

Putative Polycomb group protein ASXL3

Molecular Weight

Mass (kDA):
241.919 kDA

Genomic Context


Human

Location:	18q12.1
Sequence:	18; NC_000018.10 (33578219..33751195)

Tissue Specificity

Expressed in pancreatic islets, testis, neuroblastoma, head and neck tumor.

Subcellular Localizations

Nucleus.

Diseases

Bainbridge-Ropers syndrome (BRPS)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASXL3

References

PMID: 15138607 by Katoh M., et al. Identification and characterization of ASXL3 gene in silico.

PMID: 23383720 by Bainbridge M.N., et al. De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome.