This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Cysteine protease ATG4B Antibodies
AND ATG4B ELISA kits, Cysteine protease ATG4B Proteins
Many biological assays use antibodies to detect Cysteine protease ATG4B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cysteine protease ATG4B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cysteine protease ATG4B antibodies...
Designing a Western blot for Cysteine protease ATG4B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ATG4B Western Blot GuideATG4B Infographic by Boster Bio
All ATG4B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M02885
100 μl
Cat # M02885
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02885-2
100 µg/vial
Cat # A02885-2
100 µg/vial
Anti-SSTR5 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M02892-1
100 μl/vial
Cat # M02892-1
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # M02891-1
100 μl/vial
Cat # M02891-1
100 μl/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A02885
0.1 mg
Cat # A02885
0.1 mg
Human, Mouse, Rat
IHC, WB
$523
Cat # M02885-1
100 µl
Cat # M02885-1
100 µl
ATG4B Overview
Facts about Cysteine protease ATG4B.
Cysteine protease ATG4B (ATG4B)
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to show a C-terminal glycine.
Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation into phosphatidylethanolamine (PE) and insertion to membranes, which is essential for autophagy. Has also an activity of delipidating receptor to the PE-conjugated forms.
Gene Information
| Human | |
|---|---|
| Gene Name: | ATG4B |
| Uniprot: | Q9Y4P1 |
| Entrez: | 23192 |
Family
| Belongs to: |
|---|
| peptidase C54 family |
Alternative Names
APG4 autophagy 4 homolog B (S. cerevisiae); APG4 autophagy 4 homolog B; Apg4B; ATG4 autophagy related 4 homolog B (S. cerevisiae); ATG4B; AUTL1; AUTL1MGC1353; AUT-like 1 cysteine endopeptidase; autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; cysteine protease ATG4B; DKFZp586D1822; EC 3.4.22; EC 3.4.22.-; hAPG4B; KIAA0943
Molecular Weight
Mass (kDA):
44.294 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.3 |
| Sequence: | 2; NC_000002.12 (241637659..241673857) |
Tissue Specificity
Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
Subcellular Localizations
Cytoplasm.
Diseases
- Nerve Degeneration
- Reperfusion Injury
- Malignant Neoplasms
- Retinal Diseases
- Equilibration Disorder
- Glaucoma
- Virus Diseases
- Lung Injury
- Liver Diseases
- Aneurysm
- Neurodegenerative Disorders
- Liver Damage
Interacting Proteins
- GABARAP
- GABARAPL1
- GABARAPL2
- MAP1LC3A
- MAP1LC3B
- MAP1LC3C
Pathways
- Autophagy
- Cell Death
- Conjugation
- Cellular Homeostasis
- Secretion
- Programmed Cell Death
- Proteolysis
- Equilibrioception
- Phagocytosis
- Catabolic Process
- Rna Interference
- Cellular Process
- Inner Ear Development
PTMs
- Cleavage
Research Areas
- Autophagy
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATG4B
bosterbio.com/bosterbio-gene-info-cards/ATG4B
References
PMID: 12446702 by Marino G., et al. Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.
PMID: 15169837 by Kabeya Y., et al. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.