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- Table of Contents
Facts about V-type proton ATPase 116 kDa subunit a isoform 1.
Required for assembly and activity of the vacuolar ATPase.
Potential role in differential targeting and regulation of this enzyme for a specific organelle (By similarity).. .
Human | |
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Gene Name: | ATP6V0A1 |
Uniprot: | Q93050 |
Entrez: | 535 |
Belongs to: |
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V-ATPase 116 kDa subunit family |
a1; ATP6N1; ATP6N1AATPase, H+ transporting, lysosomal non-catalytic accessory protein 1(110/116kD); ATP6V0; ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalyticaccessory protein 1A (110/116kD); ATPase, H+ transporting, lysosomal V0 subunit a isoform 1; ATPase, H+ transporting, lysosomal V0 subunit a1; Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit; DKFZp781J1951; Stv1; Vacuolar adenosine triphosphatase subunit Ac116; Vacuolar proton pump subunit 1; vacuolar proton pump, subunit 1; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1; vacuola
Mass (kDA):
96.413 kDA
Human | |
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Location: | 17q21.2 |
Sequence: | 17; NC_000017.11 (42458874..42522579) |
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Coated vesicle. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PMID: 12643545 by Basrur V., et al. Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.
PMID: 28024296 by Matsumoto A., et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.