ATP7A Antibodies

AND ATP7A ELISA kits, ATP7A Proteins

Many biological assays use antibodies to detect ATP7A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP7A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP7A antibodies...

We validate the specificity of these antibodies to ATP7A by testing them on tissues known to express ATP7A positively and negatively. Browse below to find the ATP7A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP7A Infographic by Boster Bio

All ATP7A Products

Product

Figures

Specificity

Applications

Price

Anti-ATP7A (H640) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A01085
100ul

ATP7A Overview

Facts about Copper-transporting ATPase 1.

ATP7A 3D structure. Source: alphafold

Copper-transporting ATPase 1 (ATP7A)

May supply copper to copper-requiring proteins within the secretory pathway, when localized at the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

Gene Information

Human
Gene Name:	ATP7A
Uniprot:	Q04656
Entrez:	538

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

ATPase, Cu++ transporting, alpha polypeptide; Copper pump 1; copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; EC 3.6.3; EC 3.6.3.4; MC1; Menkes disease-associated protein; Menkes syndrome; MK; MNKFLJ17790; OHS; SMAX3

Molecular Weight

Mass (kDA):
163.373 kDA

Genomic Context


Human

Location:	Xq21.1
Sequence:	X; NC_000023.11 (77910656..78050395)

Tissue Specificity

Found in most tissues except liver. Isoform 3 is widely expressed including in liver cell lines. Isoform 1 is expressed in fibroblasts, choriocarcinoma, colon carcinoma and neuroblastoma cell lines. Isoform 2 is expressed in fibroblasts, colon carcinoma and neuroblastoma cell lines.

Subcellular Localizations

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cycles constitutively between the trans-Golgi network (TGN) and the plasma membrane (PubMed:9147644). Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels.; [Isoform 3]: Cytoplasm, cytosol.; [Isoform 5]: Endoplasmic reticulum.