Ataxin-1 Antibodies

AND ATXN1 ELISA kits, Ataxin-1 Proteins

Many biological assays use antibodies to detect Ataxin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ataxin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ataxin-1 antibodies...

We validate the specificity of these antibodies to Ataxin-1 by testing them on tissues known to express ATXN1 positively and negatively. Browse below to find the ATXN1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATXN1 Infographic by Boster Bio

All ATXN1 Products

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Anti-Ataxin 1/ATXN1 Antibody Picoband®

4 Q&As

Western blot analysis of Ataxin 1 using anti-Ataxin 1 antibody (PB9422)

IHC analysis of Ataxin 1 using anti-Ataxin 1 antibody (PB9422)

Flow Cytometry analysis of SiHa cells using anti-Ataxin 1 antibody (PB9422)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9422
100 μg/vial

Anti-Ataxin-1 ATXN1 Antibody

WesternBlot (WB) analysis of Ataxin-1 polyclonal antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A01786
100ul

Anti-Phospho-Ataxin-1 (S776) ATXN1 Antibody

Western blot analysis of lysates from HepG2 cells treated with Adriamycin 0

Immunohistochemical analysis of paraffin-embedded human liver cancer

Immunofluorescence analysis of NIH/3T3 cells, using Ataxin 1 (Phospho-Ser776) Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A01786S776
100ul

Anti-Ataxin-1 ATXN1 Antibody

Western Blot analysis of various cells using Ataxin-1 Polyclonal Antibody diluted at 1:500

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Ataxin 1 Antibody

Immunofluorescence analysis of NIH/3T3 cells, using Ataxin 1 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A01786-1
100ul

Anti-Ataxin-1 ATXN1 Monoclonal Antibody

Western Blot analysis using Ataxin-1 Monoclonal Antibody against HEK293 (1) and ATXN1-hIgGFc transfected HEK293 (2) cell lysate

Immunohistochemistry analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) with DAB staining using Ataxin-1 Monoclonal Antibody

Immunofluorescence analysis of NTERA-2 cells using Ataxin-1 Monoclonal Antibody (green)

Human

ELISA, Flow Cytometry, IF, IHC, WB

$380
Cat # M01786
100ul

Anti-Ataxin 1 Antibody Picoband® (monoclonal, 2B13G8)

Western blot analysis of Ataxin 1 using anti-Ataxin 1 antibody (M01786-1)

IHC analysis of Ataxin 1 using anti-Ataxin 1 antibody (M01786-1)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M01786-1
100 μg/vial

ATXN1 Overview

Facts about Ataxin-1.

ATXN1 3D structure. Source: alphafold

Ataxin-1 (ATXN1)

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and may help, Together with NCOR2, RBPJ-mediated repression.

Binds RNA in vitro. Might be involved in RNA metabolism (PubMed:21475249).

Gene Information

Human
Gene Name:	ATXN1
Uniprot:	P54253
Entrez:	6310

Family

Belongs to:

ATXN1 family

Alternative Names

ataxin 1; ataxin 1); ataxin-1; ATX1spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant; SCA1D6S504E; Spinocerebellar ataxia type 1 protein

Molecular Weight

Mass (kDA):
86.923 kDA

Genomic Context


Human

Location:	6p22.3
Sequence:	6; NC_000006.12 (16299112..16761490, complement)

Tissue Specificity

Widely expressed throughout the body.

Subcellular Localizations

Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus.

Diseases

Ataxia, Spinocerebellar
Ataxia
Opca, Menzel Type
Neurodegenerative Disorders
Trinucleotide Repeat Expansion
Nerve Degeneration
Cerebellar Ataxia
Neuropathology Disease
Haploinsufficiency
Eye Abnormalities
Congenital Heart Defects
Alzheimer's Disease

Malnutrition
Ophthalmoplegia
Atrophy
Muscle Hypotonia
Impaired Cognition
Chronic Lymphocytic Leukemia

Pathways

Pathogenesis
Cell Death
Localization
Transport
Cell Development
Aging
Dna Repair
Synaptic Transmission
Plasma Cell Differentiation
Nuclear Export

Cell Differentiation
Histone Acetylation
Rna Interference
Oncogenesis

PTMs

Phosphorylation
Cleavage

Acetylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATXN1

References

PMID: 7951322 by Banfi S., et al. Identification and characterization of the gene causing type 1 spinocerebellar ataxia.

PMID: 8634720 by Quan F., et al. A novel CAG repeat configuration in the SCA1 gene: implications for the molecular diagnostics of spinocerebellar ataxia type 1.