Ataxin-1 Antibodies

Ataxin-1 (ATXN1)

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and may help, Together with NCOR2, RBPJ-mediated repression.

Binds RNA in vitro. Might be involved in RNA metabolism (PubMed:21475249).

Gene Information

Human
Gene Name:	ATXN1
Uniprot:	P54253
Entrez:	6310

Family

Belongs to:
ATXN1 family

Alternative Names

ataxin 1; ataxin 1); ataxin-1; ATX1spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant; SCA1D6S504E; Spinocerebellar ataxia type 1 protein

Molecular Weight

Mass (kDA):
86.923 kDA

Genomic Context

Human
Location:	6p22.3
Sequence:	6; NC_000006.12 (16299112..16761490, complement)

Tissue Specificity

Widely expressed throughout the body.

Subcellular Localizations

Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus.

Diseases

• Ataxia, Spinocerebellar
• Ataxia
• Opca, Menzel Type
• Neurodegenerative Disorders
• Trinucleotide Repeat Expansion
• Nerve Degeneration
• Cerebellar Ataxia
• Neuropathology Disease
• Haploinsufficiency
• Eye Abnormalities
• Congenital Heart Defects
• Alzheimer's Disease

• Malnutrition
• Ophthalmoplegia
• Atrophy
• Muscle Hypotonia
• Impaired Cognition
• Chronic Lymphocytic Leukemia

Pathways

• Pathogenesis
• Cell Death
• Localization
• Transport
• Cell Development
• Aging
• Dna Repair
• Synaptic Transmission
• Plasma Cell Differentiation
• Nuclear Export

• Cell Differentiation
• Histone Acetylation
• Rna Interference
• Oncogenesis

PTMs

• Phosphorylation
• Cleavage

• Acetylation
• Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATXN1

Boster Bio - Best Uses Of The ATXN1 Marker

If you are interested in finding the best ATXN1 antibody, you may be wondering where to buy it. In this article, we will give you an overview of the Boster Bio research primary and secondary antibodies, as well as ELISA kits. The best antibody for this research marker is the Boster Bio Anti-ATXN7L1 antibody. Boster is a leading manufacturer of antibodies for various types of research.

Boster Bio Anti-ATXN7L1 Antibody

The anti-ATXN7L1 antibody from Boster Bio reacts with the ATXN1 marker and can be used for a number of applications. The product can be stored at 4degC for up to a month. This product is compatible with Human and Mouse. The manufacturer states that the product is compatible with all species. Furthermore, it can be used for research in a variety of biological samples.

Boster Bio's research primary and secondary antibodies

Immunohistochemistry is a specialized process of staining cell tissues to detect antigens or haptens in a given sample. Boster Bio optimizes their antibodies to match the specific dilution ratio, tissue type, and assay. Multiplex Immunohistochemistry services allow the detection of multiple targets and deliver high throughput during screening and assay processing. Depending on the needs of the customer, Boster Bio can also produce antibodies for any type of tissue sample, including blood, skin, and urine.

The company offers over 16,000 antibodies, including antibodies that are validated for ELISA, FC, and WB. Boster Bio also offers rabbit polyclonal antibodies and provides a free secondary antibody with primary antibody purchases. In addition to offering antibodies for ELISA, Boster Bio offers rabbit polyclonal and human antibodies. All Boster Bio antibodies are guaranteed to retain their biological activity and perform as advertised.

In addition to research primary and secondary antibodies, Boster produces high-quality ELISA kits. These kits can be used to detect biomarkers in cancer, neuroscience, developmental biology, and inflammation. Their sensitivity is picogram-level. Additionally, Boster manufactures immunological reagents through tebu-bio. All Boster research primary and secondary antibodies are produced in-house to ensure quality.

The company also produces ELISA kits and research reagents for various applications. Boster Bio's research primary and secondary antibodies include a variety of phospho-antibodies. The company has over 500 phospho-antibodies in its inventory. The company also produces ELISA kits, high-specific antibodies, and phospho-antibodies. The company has also launched a number of clinical trials for its antibodies.

The research primary and secondary antibodies are essential for detecting different antigens. They are obtained through immunization of host animals with antibodies of various species. Secondary antibodies recognize the immunoglobulin (Ig) domain of primary antibodies, and assist in purification, sorting, and detection of target antigens. Most of them are conjugated with a label, which determines their conjugation state and choice.

Boster Bio's research ELISA kits

Researchers looking to test the effects of vaccines and other therapeutic agents can use one of Boster Bio's research ELISA kit for ATXN1. This assay kit for ATXN1 detection uses antibodies to interact with the ATXN1 antigen to detect the protein in biological samples. The MBS060290 kit is sensitive and specific enough to detect Ataxin 1 in serum, undiluted body fluids, and tissue homogenates. The ELISA kit for this marker contains quantitative QC assays for reproducibility.