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- Table of Contents
Facts about Ataxin-7-like protein 3.
The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972).
Human | |
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Gene Name: | ATXN7L3 |
Uniprot: | Q14CW9 |
Entrez: | 56970 |
Belongs to: |
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SGF11 family |
Ataxin-7-like protein 3
Mass (kDA):
38.651 kDA
Human | |
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Location: | 17q21.31 |
Sequence: | 17; NC_000017.11 (44191805..44198161, complement) |
Nucleus.
PMID: 18206972 by Zhao Y., et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
PMID: 21746879 by Lang G., et al. The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements.