AUP1 Antibodies

AND AUP1 ELISA kits, AUP1 Proteins

Many biological assays use antibodies to detect AUP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AUP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AUP1 antibodies...

We validate the specificity of these antibodies to AUP1 by testing them on tissues known to express AUP1 positively and negatively. Browse below to find the AUP1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AUP1 Infographic by Boster Bio

All AUP1 Products

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Anti-AUP1 Antibody Picoband®

Western blot analysis of AUP1 using anti-AUP1 antibody (A08937-1)

Flow Cytometry analysis of U937 cells using anti-AUP1 antibody (A08937-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08937-1
100 μg/vial

AUP1 Overview

Facts about Ancient ubiquitous protein 1.

AUP1 3D structure. Source: alphafold

Ancient ubiquitous protein 1 (AUP1)

May play a role in the translocation of terminally misfolded proteins in the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. .

Gene Information

Human
Gene Name:	AUP1
Uniprot:	Q9Y679
Entrez:	550

Family

Belongs to:

AUP1 family

Alternative Names

ancient ubiquitous protein 1

Molecular Weight

Mass (kDA):
45.787 kDA

Genomic Context


Human

Location:	2p13.1
Sequence:	2; NC_000002.12 (74526652..74529706, complement)

Tissue Specificity

Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.

Diseases

Dislocations
Cytomegalovirus Infections
Cystic Fibrosis
Proteostasis Deficiencies
Liver Carcinoma
Liver Neoplasms

Interacting Proteins

OPRM1

Pathways

Localization
Autophagy
Aging
Lipid Storage

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AUP1

References

PMID: 12042322 by Kato A., et al. Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3.

PMID: 18711132 by Mueller B., et al. SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.