AWAT2 Antibodies

AND AWAT2 ELISA kits, AWAT2 Proteins

Many biological assays use antibodies to detect AWAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AWAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AWAT2 antibodies...

We validate the specificity of these antibodies to AWAT2 by testing them on tissues known to express AWAT2 positively and negatively. Browse below to find the AWAT2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AWAT2 Infographic by Boster Bio

All AWAT2 Products

Product

Figures

Specificity

Applications

Price

Anti-AWAT2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A12143
100ul

AWAT2 Overview

Facts about Acyl-CoA wax alcohol acyltransferase 2.

AWAT2 3D structure. Source: alphafold

Acyl-CoA wax alcohol acyltransferase 2 (AWAT2)

Acyltransferase that mostly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin.

Has no action using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl- CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this action is unclear in vivo.

Gene Information

Human
Gene Name:	AWAT2
Uniprot:	Q6E213
Entrez:	158835

Family

Belongs to:

diacylglycerol acyltransferase family

Alternative Names

acyl-CoA wax alcohol acyltransferase 2

Molecular Weight

Mass (kDA):
38.094 kDA

Genomic Context


Human

Location:	Xq13.1
Sequence:	X; NC_000023.11 (70040542..70049970, complement)

Tissue Specificity

Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Obesity
Atherosclerosis

Pathways

Lipid Binding

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AWAT2

References

PMID: 15220349 by Cheng J.B., et al. Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.

PMID: 14970677 by Winter A., et al. Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals.