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- Table of Contents
ACAT1 Antibodies
AND ACAT1 ELISA kits, ACAT1 Proteins
Many biological assays use antibodies to detect ACAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACAT1 antibodies...
Designing a Western blot for ACAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACAT1 Western Blot GuideDesigning an IHC experiment for ACAT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ACAT1 IHC GuideACAT1 Infographic by Boster Bio
All ACAT1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02008-1
100 µg/vial
Cat # A02008-1
100 µg/vial
ACAT1 Overview
Facts about Acetyl-CoA acetyltransferase, mitochondrial.
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1)
Plays a significant role in ketone body metabolism. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ACAT1 |
| Uniprot: | P24752 |
| Entrez: | 38 |
Family
| Belongs to: |
|---|
| thiolase-like superfamily |
Alternative Names
ACAT; ACAT1; acetoacetyl Coenzyme A thiolase; Acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase 1; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; EC 2.3.1; EC 2.3.1.9; MAT; mitochondrial acetoacetyl-CoA thiolase; T2; THIL
Molecular Weight
Mass (kDA):
45.2 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q22.3 |
| Sequence: | 11; NC_000011.10 (108116705..108148822) |
Subcellular Localizations
Mitochondrion.
Diseases
- Atherosclerosis
- Hypercholesterolemia
- Cardiovascular Diseases
- Arteriosclerosis
- Alzheimer's Disease
- Hyperlipidemia
- Malignant Neoplasms
- Neoplasms
- Hypertensive Disease
- Liver Carcinoma
- Dental Plaque
- Atheroma
Pathways
- Cholesterol Homeostasis
- Secretion
- Cholesterol Esterification
- Cholesterol Efflux
- Intestinal Cholesterol Absorption
- Localization
- Translation
- Lipid Homeostasis
- Excretion
- Cell Adhesion
- Transport
- Cell Death
- Pathogenesis
PTMs
- Acetylation
- Phosphorylation
- Cleavage
Research Areas
- Cancer
- Cellular Markers
- Lipid and Metabolism
- Mitochondrial Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACAT1
bosterbio.com/bosterbio-gene-info-cards/ACAT1
References
PMID: 1979337 by Fukao T., et al. Molecular cloning and sequence of the complementary DNA encoding human mitochondrial acetoacetyl-coenzyme A thiolase and study of the variant enzymes in cultured fibroblasts from patients with 3- ketothiolase deficiency.
PMID: 1684944 by Kano M., et al. Structure and expression of the human mitochondrial acetoacetyl-CoA thiolase-encoding gene.