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- Table of Contents
Facts about Aldehyde oxidase 4.
Is devoid of pyridoxal-oxidizing activity, compared to another aldehyde oxidases. Acts as a negative modulator of the epidermal trophism.
| Mouse | |
|---|---|
| Gene Name: | Aox4 |
| Uniprot: | Q3TYQ9 |
| Entrez: | 71872 |

| Belongs to: |
|---|
| xanthine dehydrogenase family |

Aldehyde oxidase 4
Mass (kDA):
148.279 kDA

| Mouse | |
|---|---|
| Location: | 1 C1.3|1 28.97 cM |
| Sequence: | 1; |
Highly expressed in Harderian glands and sebaceous glands with detectable levels in the epidermis and other keratinized epithelia (at protein level). Detected in testis. The expression is 3 times greater in females than in males.

PMID: 11562361 by Terao M., et al. Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1.
PMID: 18981221 by Terao M., et al. Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the biosynthesis of retinoic acid: generation and characterization of a knockout mouse.