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- Table of Contents
Facts about BAG family molecular chaperone regulator 2.
Co-chaperone for HSP70 and HSC70 chaperone proteins.
Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release (PubMed:24318877, PubMed:9873016)..
| Human | |
|---|---|
| Gene Name: | BAG2 |
| Uniprot: | O95816 |
| Entrez: | 9532 |

| Belongs to: |
|---|
| No superfamily |

BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bcl-2-associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); dJ417I1.2; KIAA0576; MGC149462
Mass (kDA):
23.772 kDA

| Human | |
|---|---|
| Location: | 6p12.1 |
| Sequence: | 6; NC_000006.12 (57172326..57189833) |





PMID: 9873016 by Takayama S., et al. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.
PMID: 24318877 by Rauch J.N., et al. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.