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- Table of Contents
Designing a Western blot for BAG2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BAG2 Western Blot GuideFacts about BAG family molecular chaperone regulator 2.
Co-chaperone for HSP70 and HSC70 chaperone proteins.
Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release (PubMed:24318877, PubMed:9873016)..
| Human | |
|---|---|
| Gene Name: | BAG2 |
| Uniprot: | O95816 |
| Entrez: | 9532 |

| Belongs to: |
|---|
| No superfamily |

BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bcl-2-associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); dJ417I1.2; KIAA0576; MGC149462
Mass (kDA):
23.772 kDA

| Human | |
|---|---|
| Location: | 6p12.1 |
| Sequence: | 6; NC_000006.12 (57172326..57189833) |





PMID: 9873016 by Takayama S., et al. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.
PMID: 24318877 by Rauch J.N., et al. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.