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- Table of Contents
Designing a Western blot for Bcl-2-related protein A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BCL2A1 Western Blot GuideFacts about Bcl-2-related protein A1.
Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity). .
| Human | |
|---|---|
| Gene Name: | BCL2A1 |
| Uniprot: | Q16548 |
| Entrez: | 597 |

| Belongs to: |
|---|
| Bcl-2 family |

ACC-1; ACC-2; Bcl-2 related protein A1; BCL2A1; Bcl2L5; Bcl2-L-5; BCL2L5HBPA1; Bcl-2-like protein 5; BCL2-related protein A1; Bfl-1; BFL1bcl-2-related protein A1; GRS; GRSbcl2-L-5; hematopoietic BCL2-related protein A1; Hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Mass (kDA):
20.132 kDA

| Human | |
|---|---|
| Location: | 15q25.1 |
| Sequence: | 15; NC_000015.10 (79960892..79971196, complement) |
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
Cytoplasm.






PMID: 7478596 by Choi S.S., et al. A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow.
PMID: 8605321 by Karsan A., et al. Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells.