B-cell lymphoma 3 protein Antibodies

AND BCL3 ELISA kits, B-cell lymphoma 3 protein Proteins

Many biological assays use antibodies to detect B-cell lymphoma 3 protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B-cell lymphoma 3 protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B-cell lymphoma 3 protein antibodies...

We validate the specificity of these antibodies to B-cell lymphoma 3 protein by testing them on tissues known to express BCL3 positively and negatively. Browse below to find the BCL3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BCL3 Infographic by Boster Bio

All BCL3 Products

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Specificity

Applications

Price

Anti-B-cell lymphoma 3 protein BCL3 Antibody

Human

ELISA, WB

$449
Cat # A02773
0.1 mg

Anti-BCL3 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02773-3
100 μg/vial

BCL3 (NM_005178) Human Recombinant Protein

$813
Cat # PROTP20749
20 µg

BCL3 (NM_005178) Human Over-expression Lysate

Human

$628
Cat # LS000602
100 µg

Anti-BCL3 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02773-4
100 µg/vial

BCL3 Overview

Facts about B-cell lymphoma 3 protein.

BCL3 3D structure. Source: alphafold

B-cell lymphoma 3 protein (BCL3)

Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit.

In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).

Gene Information

Human
Gene Name:	BCL3
Uniprot:	P20749
Entrez:	602

Family

Belongs to:

No superfamily

Alternative Names

B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3-encoded protein; BCL-3; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3

Molecular Weight

Mass (kDA):
47.584 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (44742620..44760044)

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.

Diseases

Lymphoma
Leukemia
Chronic Lymphocytic Leukemia
Lymphoid Leukemia
Neoplasms
B-cell Lymphomas
Chromosomal Translocation
Cleft Palate
Malignant Neoplasms
Cleft Lip
Leukemia, B-cell
Trisomy

Dysequilibrium Syndrome
Malignant Paraganglionic Neoplasm
Diffuse Large B-cell Lymphoma
Cytogenetic Abnormality
Congenital Abnormality
Lymphoma, Non-hodgkin
Hodgkin Disease

Interacting Proteins

BCL10
CTBP2
LCK

Pathways

Pathogenesis
Interphase
Localization
Cell Cycle
Cell Proliferation
Cell Death
Cell Growth
Immune Response
Inflammatory Response
Translation
Muscle Atrophy
Rna Interference
Secretion

Skeletal Muscle Atrophy
Cell Adhesion
Cell Activation
Cell Migration
Cellular Homeostasis
Proteolysis
Hypersensitivity

PTMs

Phosphorylation

Methylation

Research Areas

Adaptive Immunity
Cell Cycle and Replication
Immunology
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCL3

References

PMID: 2180580 by Ohno H., et al. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control.

PMID: 7896265 by McKeithan T.W., et al. Genomic structure of the candidate proto-oncogene BCL3.