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B-cell lymphoma 3 protein Antibodies
AND BCL3 ELISA kits, B-cell lymphoma 3 protein Proteins
Many biological assays use antibodies to detect B-cell lymphoma 3 protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B-cell lymphoma 3 protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B-cell lymphoma 3 protein antibodies...
Designing a Western blot for B-cell lymphoma 3 protein? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BCL3 Western Blot GuideBCL3 Infographic by Boster Bio
All BCL3 Products
Product
Figures
Specificity
Applications
Price
Anti-BCL3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02773-4
100 µg/vial
Cat # A02773-4
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02773-3
100 μg/vial
Cat # A02773-3
100 μg/vial
BCL3 Overview
Facts about B-cell lymphoma 3 protein.
B-cell lymphoma 3 protein (BCL3)
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit.
In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | BCL3 |
| Uniprot: | P20749 |
| Entrez: | 602 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3-encoded protein; BCL-3; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3
Molecular Weight
Mass (kDA):
47.584 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.32 |
| Sequence: | 19; NC_000019.10 (44742620..44760044) |
Subcellular Localizations
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Diseases
- Lymphoma
- Leukemia
- Chronic Lymphocytic Leukemia
- Lymphoid Leukemia
- Neoplasms
- B-cell Lymphomas
- Chromosomal Translocation
- Cleft Palate
- Malignant Neoplasms
- Cleft Lip
- Leukemia, B-cell
- Trisomy
Interacting Proteins
- BCL10
- CTBP2
- LCK
Pathways
- Pathogenesis
- Interphase
- Localization
- Cell Cycle
- Cell Proliferation
- Cell Death
- Cell Growth
- Immune Response
- Inflammatory Response
- Translation
- Muscle Atrophy
- Rna Interference
- Secretion
PTMs
- Phosphorylation
Research Areas
- Adaptive Immunity
- Cell Cycle and Replication
- Immunology
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCL3
bosterbio.com/bosterbio-gene-info-cards/BCL3
References
PMID: 2180580 by Ohno H., et al. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control.
PMID: 7896265 by McKeithan T.W., et al. Genomic structure of the candidate proto-oncogene BCL3.