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- Table of Contents
BCLAF1 Antibodies
AND BCLAF1 ELISA kits, BCLAF1 Proteins
Many biological assays use antibodies to detect BCLAF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCLAF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCLAF1 antibodies...
Designing a Western blot for BCLAF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BCLAF1 Western Blot GuideDesigning an IHC experiment for BCLAF1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the BCLAF1 IHC GuideBCLAF1 Infographic by Boster Bio
All BCLAF1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A04100-3
100 μg/vial
Cat # A04100-3
100 μg/vial
BCLAF1 Overview
Facts about Bcl-2-associated transcription factor 1.
Bcl-2-associated transcription factor 1 (BCLAF1)
Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability throughout the SNARP complex which associates with the 3'end of the CCND1 gene and its mRNA.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | BCLAF1 |
| Uniprot: | Q9NYF8 |
| Entrez: | 9774 |
Family
| Belongs to: |
|---|
| BCLAF1/THRAP3 family |
Alternative Names
bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Btf; BTFKIAA0164bK211L9.1
Molecular Weight
Mass (kDA):
106.122 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q23.3 |
| Sequence: | 6; NC_000006.12 (136256627..136289851, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Muscular Dystrophy, Emery-dreifuss
- Carcinoma
- Dystrophy
- Muscular Dystrophy
- Adenoma
- Neoplasm Invasiveness
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Prostatic Neoplasms
- Bone Neoplasms
Interacting Proteins
- BCL2
- EMD
Pathways
- Cell Death
- Localization
- Cell Proliferation
- Transport
- Programmed Cell Death
- Lung Development
- Regulation Of Gene Expression
- Cell Cycle
- Rna Processing
- Pathogenesis
- Protein Phosphorylation
- Cell Activation
- Cell Migration
PTMs
- Phosphorylation
- Demethylation
- Cleavage
Research Areas
- Apoptosis
- DNA Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCLAF1
bosterbio.com/bosterbio-gene-info-cards/BCLAF1
References
PMID: 10330179 by Kasof G.M., et al. Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.
PMID: 15009215 by Haraguchi T., et al. Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.