BHMT Antibodies

AND BHMT ELISA kits, BHMT Proteins

Many biological assays use antibodies to detect BHMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BHMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BHMT antibodies...

We validate the specificity of these antibodies to BHMT by testing them on tissues known to express BHMT positively and negatively. Browse below to find the BHMT antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BHMT Infographic by Boster Bio

All BHMT Products

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Specificity

Applications

Price

Anti-BHMT Monoclonal Antibody

Immunohistochemistry validation of BHMT using Anti-BHMT Monoclonal Antibody (M06712)

Human

ELISA, IF, IHC, WB

$380
Cat # M06712
100ul

Anti-BHMT Antibody Picoband®

Western blot analysis of BHMT using anti-BHMT antibody (A06712-1)

Flow Cytometry analysis of HEPG2 cells using anti-BHMT antibody (A06712-1)

Flow Cytometry analysis of U937 cells using anti-BHMT antibody (A06712-1)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A06712-1
100 μg/vial

Human BHMT/Betaine-homocysteine methyltransferase Recombinant Protein

SDS-PAGE

$234
Cat # PROTQ93088
Starting from 20ug

Anti-BHMT Mouse Monoclonal Antibody [Clone ID: OTI3E11]

Western blot analysis of extracts (10ug) from 1 cell line by using anti-BHMT monoclonal antibody (1:200)

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-BHMT mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-BHMT mouse monoclonal antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M06712-1
100 µl

Anti-BHMT Antibody Picoband®

Western blot analysis of BHMT using anti-BHMT antibody (A06712-2)

IHC analysis of BHMT using anti-BHMT antibody (A06712-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06712-2
100 μg/vial

Anti-BHMT Rabbit Monoclonal Antibody

Human

IP, IHC, WB

$370
Cat # M06712-2
100 μl/vial

BHMT (NM_001713) Human Over-expression Lysate

Human

$628
Cat # LS000635
20 µg, 100 µg

BHMT Overview

Facts about Betaine--homocysteine S-methyltransferase 1.

BHMT 3D structure. Source: alphafold

Betaine--homocysteine S-methyltransferase 1 (BHMT)

Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively.

This reaction is also required for the irreversible oxidation of choline. .

Gene Information

Human
Gene Name:	BHMT
Uniprot:	Q93088
Entrez:	635

Family

Belongs to:

No superfamily

Alternative Names

betaine homocysteine methyltransferase; betaine-homocysteine methyltransferase; betaine--homocysteine S-methyltransferase 1; betaine--homocysteine S-methyltransferase; BHMT1; EC 2.1.1; EC 2.1.1.5

Molecular Weight

Mass (kDA):
44.998 kDA

Genomic Context


Human

Location:	5q14.1
Sequence:	5; NC_000005.10 (79111809..79132288)

Subcellular Localizations

Cytoplasm.

Diseases

5,10-methylenetetrahydrofolate Reductase Deficiency
Hyperhomocysteinemia
Cardiovascular Diseases
Malignant Neoplasms
Liver Carcinoma
Vascular Diseases
Carcinoma
Neoplasms
Folic Acid Deficiency
Fatty Liver
Diabetes Mellitus
Congenital Abnormality
Thrombosis

Cleft Palate
Liver Diseases
Steatosis
Liver Neoplasms
Carcinogenesis
Cleft Lip
Disease Of Adrenal Medulla

Pathways

Methylation
Dna Methylation
Transsulfuration
Transport
Secretion
Proteolysis
Pathogenesis
Excretion
Cell Death
Autophagy
Aging
Macroautophagy
Cell Proliferation

Response To Alcohol
Localization
Dna Hypomethylation
Amino Acid Homeostasis
Nodulation
Reverse Transcription
Mrna Transcription

PTMs

Methylation
Oxidation

Reduction
Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BHMT

References

PMID: 8798461 by Garrow T.A.; Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase.

PMID: 10075673 by Park E.I., et al. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene.