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- Table of Contents
BHMT Antibodies
AND BHMT ELISA kits, BHMT Proteins
Many biological assays use antibodies to detect BHMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BHMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BHMT antibodies...
Designing a Western blot for BHMT? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BHMT Western Blot GuideBHMT Infographic by Boster Bio
All BHMT Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06712-2
100 μg/vial
Cat # A06712-2
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A06712-1
100 μg/vial
Cat # A06712-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M06712-1
100 µl
Cat # M06712-1
100 µl
SDS-PAGE
$234
Cat # PROTQ93088
Starting from 20ug
Cat # PROTQ93088
Starting from 20ug
BHMT Overview
Facts about Betaine--homocysteine S-methyltransferase 1.
Betaine--homocysteine S-methyltransferase 1 (BHMT)
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively.
This reaction is also required for the irreversible oxidation of choline. .
Gene Information
| Human | |
|---|---|
| Gene Name: | BHMT |
| Uniprot: | Q93088 |
| Entrez: | 635 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
betaine homocysteine methyltransferase; betaine-homocysteine methyltransferase; betaine--homocysteine S-methyltransferase 1; betaine--homocysteine S-methyltransferase; BHMT1; EC 2.1.1; EC 2.1.1.5
Molecular Weight
Mass (kDA):
44.998 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q14.1 |
| Sequence: | 5; NC_000005.10 (79111809..79132288) |
Subcellular Localizations
Cytoplasm.
Diseases
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Hyperhomocysteinemia
- Cardiovascular Diseases
- Malignant Neoplasms
- Liver Carcinoma
- Vascular Diseases
- Carcinoma
- Neoplasms
- Folic Acid Deficiency
- Fatty Liver
- Diabetes Mellitus
- Congenital Abnormality
- Thrombosis
Pathways
- Methylation
- Dna Methylation
- Transsulfuration
- Transport
- Secretion
- Proteolysis
- Pathogenesis
- Excretion
- Cell Death
- Autophagy
- Aging
- Macroautophagy
- Cell Proliferation
PTMs
- Methylation
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BHMT
bosterbio.com/bosterbio-gene-info-cards/BHMT
References
PMID: 8798461 by Garrow T.A.; Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase.
PMID: 10075673 by Park E.I., et al. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene.