BICC1 Antibodies

AND BICC1 ELISA kits, BICC1 Proteins

Many biological assays use antibodies to detect BICC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BICC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BICC1 antibodies...

We validate the specificity of these antibodies to BICC1 by testing them on tissues known to express BICC1 positively and negatively. Browse below to find the BICC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BICC1 Infographic by Boster Bio

All BICC1 Products

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Product

Figures

Specificity

Applications

Price

Anti-BICC1 Antibody (N-term)

Western blot analysis of lysate from A549 cell line, using BICC1 Antibody (N-term)

Human

$299
Cat # A06638
80 µl

BICC1 (NM_001080512) Human Over-expression Lysate

Human

$960
Cat # LS080114
20 µg, 100 µg

BICC1 Overview

Facts about Protein bicaudal C homolog 1.

BICC1 3D structure. Source: alphafold

Protein bicaudal C homolog 1 (BICC1)

Putative RNA-binding protein.
Acts as a negative regulator of Wnt signaling.

May be involved in regulating gene expression during embryonic development. .

Gene Information

Human
Gene Name:	BICC1
Uniprot:	Q9H694
Entrez:	80114

Family

Belongs to:

BicC family

Alternative Names

bicaudal C homolog 1 (Drosophila); BICC; DKFZp686I21119

Molecular Weight

Mass (kDA):
104.844 kDA

Genomic Context


Human

Location:	10q21.1
Sequence:	10; NC_000010.11 (58512872..58831435)

Subcellular Localizations

Cytoplasm.

Diseases

Polycystic Kidney Diseases
Kidney Diseases
Cystic Kidney Diseases
Major Depressive Disorder
Depressive Disorder
Renal Dysplasia
Male Infertility
Autosomal Recessive Polycystic Kidney Disease
Ataxia
Kidney Failure, Chronic
Tissue Adhesions
Infertility

Hydrocephalus
Diabetes Mellitus
Polycystic Kidney, Autosomal Dominant
Growth Retardation
Mental Disorders
Dysplasia
Tremor, Unspecified

Pathways

Actin Cytoskeleton Organization
Cell Proliferation
Pancreas Development
Gene Silencing
Mitosis
Mesoderm Formation
Kidney Morphogenesis
Spermatogenesis
Cardiac Cell Differentiation
Cytoskeleton Organization

Translation
Cell Differentiation
Pathogenesis
Cell-cell Adhesion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BICC1

References

PMID: 21922595 by Kraus M.R., et al. Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia.

PMID: 24501278 by Lee H., et al. Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation.