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- Table of Contents
Btbd10 Antibodies
AND Btbd10 ELISA kits, Btbd10 Proteins
Many biological assays use antibodies to detect Btbd10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Btbd10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Btbd10 antibodies...
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Btbd10 Infographic by Boster Bio
All Btbd10 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$523
Cat # M12153
100 µl
Cat # M12153
100 µl
Btbd10 Overview
Facts about BTB/POZ domain-containing protein 10.
BTB/POZ domain-containing protein 10 (Btbd10)
Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the development of pancreatic beta cells.
.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Btbd10 |
| Uniprot: | Q80X66 |
| Entrez: | 68815 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BTB (broad-complex tramtrack and bric-a-brac/pox virus and zinc finger)domain-containing protein 10; BTB (POZ) domain containing 10; BTB/POZ domain-containing protein 10; GMRP1; GMRP-1; K+ channel tetramerization protein; KSARCOSIN; MGC13007
Molecular Weight
Mass (kDA):
53.772 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 F1 |
| Sequence: | 7; |
Diseases
- Sclerosis
- Primary Lateral Sclerosis
- Amyotrophic Lateral Sclerosis
- Lung Neoplasms
- Liver Carcinoma
- Insulinoma
- Glioma
- Tissue Adhesions
- Brain Neoplasms
- Malignant Neoplasm Of Lung
- Carcinoma
Pathways
- Cell Proliferation
- Cell Death
- Cell Adhesion
- Neuroprotection
- Translation
- Locomotion
- Cell Growth
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Btbd10
bosterbio.com/bosterbio-gene-info-cards/Btbd10
References
PMID: 18160256 by Nawa M., et al. A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1- induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.
PMID: 21267538 by Wang X., et al. Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice.