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- Table of Contents
Facts about Butyrophilin-like protein 2.
.
Human | |
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Gene Name: | BTNL2 |
Uniprot: | Q9UIR0 |
Entrez: | 56244 |
Belongs to: |
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immunoglobulin superfamily |
BTL-II; BTNL2; Butyrophilin like 2; butyrophilin-like 2 (MHC class II associated); Butyrophilin-like 2
Mass (kDA):
50.436 kDA
Human | |
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Location: | 6p21.32 |
Sequence: | 6; NC_000006.12 (32393339..32408879, complement) |
Expressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus.
Membrane; Single-pass type II membrane protein. Isoform 2 is present in the nuclear, vesicle and plasma membranes, isoform 3 is found in cytoplasmic vesicle structures and is not membrane bound.
PMID: 10803852 by Stammers M., et al. BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse.
PMID: 15735647 by Valentonyte R., et al. Sarcoidosis is associated with a truncating splice site mutation in BTNL2.