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- Table of Contents
Bpifa1 Antibodies
AND Bpifa1 ELISA kits, Bpifa1 Proteins
Many biological assays use antibodies to detect Bpifa1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bpifa1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bpifa1 antibodies...
Designing a Western blot for Bpifa1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BPIFA1 Western Blot GuideBpifa1 Infographic by Boster Bio
All Bpifa1 Products
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Specificity
Applications
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Bpifa1 Overview
Facts about BPI fold-containing family A member 1.
BPI fold-containing family A member 1 (Bpifa1)
Plays a role in the innate immune responses of the upper airways. Reduce the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative germs, such as P.
aeruginosa and K.pneumoniae.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Bpifa1 |
| Uniprot: | P97361 |
| Entrez: | 18843 |
Family
| Belongs to: |
|---|
| BPI/LBP/Plunc superfamily |
Alternative Names
bA49G10.5; BPIFA1; ligand-binding protein RYA3; LPLUNC3; Lung-specific protein X; LUNX; LUNXNASG; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; palate, lung and nasal epithelium associated; palate, lung and nasal epithelium carcinoma associated; PLUNC; protein Plunc; Secretory protein in upper respiratory tracts; SPLUNC1; SPLUNC1SPURT; tracheal epithelium enriched protein; Tracheal epithelium-enriched protein; Von Ebner protein Hl
Molecular Weight
Mass (kDA):
28.625 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 2|2 H1 |
| Sequence: | 2; |
Tissue Specificity
Detected in airway epithelia (trachea and lung) and in bronchoalveolar fluid (at protein level). Upper airways, nasopharyngeal epithelium and thymus. Highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways. No expression is detected in the terminal bronchioles, respiratory bronchioles or lung alveoli.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Malignant Neoplasm Of Lung
- Inflammation
- Innate Immune Response
- Lung Neoplasms
- Lung Diseases
- Non-small Cell Lung Carcinoma
- Pneumonia
- Nasopharyngeal Neoplasms
- Cancer Of Nasopharynx
- Polyps
Pathways
- Immune Response
- Innate Immune Response
- Localization
- Secretion
- Pathogenesis
- Flight
- Transport
- Biofilm Formation
- Cellular Localization
- Cell Cycle
- Cell Differentiation
- Rna Interference
- Anion Transport
PTMs
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Bpifa1
bosterbio.com/bosterbio-gene-info-cards/Bpifa1
References
PMID: 10224143 by Weston W.M., et al. Differential display identification of plunc, a novel gene expressed in embryonic palate, nasal epithelium, and adult lung.
PMID: 11396972 by LeClair E.E., et al. Genomic organization of the mouse plunc gene and expression in the developing airways and thymus.