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C12orf65 Antibodies

AND C12orf65 ELISA kits, C12orf65 Proteins

Many biological assays use antibodies to detect C12orf65, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C12orf65 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C12orf65 antibodies...

We validate the specificity of these antibodies to C12orf65 by testing them on tissues known to express C12orf65 positively and negatively. Browse below to find the C12orf65 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C12orf65 Infographic by Boster Bio

C12orf65 protein infographic

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C12orf65 Overview

Facts about Probable peptide chain release factor C12orf65, mitochondrial.

C12orf65 3D structure

C12orf65 3D structure. Source: alphafold

Probable peptide chain release factor C12orf65, mitochondrial (C12orf65)

May act as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation from mitochondrion. May help rescuing stalled mitoribosomes during translation (By similarity).

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Gene Information

Human
Gene Name:	C12orf65
Uniprot:	Q9H3J6
Entrez:	91574

Gene Information

Family

Belongs to:

prokaryotic/mitochondrial release factor family

Family

Alternative Names

chromosome 12 open reading frame 65; COXPD7; FLJ38663; probable peptide chain release factor C12orf65, mitochondrial

Molecular Weight

Mass (kDA):
18.828 kDA

Molecular Weight

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (123233436..123257960)

Subcellular Localizations

Mitochondrion.

Subcellular Localization

Diseases

Optic Atrophy
Atrophy
Ophthalmoplegia
Paraplegia
Spastic Paraplegia
Neurodegenerative Disorders
Spastic Paraplegia, Hereditary

Leigh Disease

Disease

Pathways

Translation
Mitochondrial Translation
Cell Proliferation
Oxidative Phosphorylation

Pathways

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For details, visit:
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References

PMID: 20598281 by Antonicka H., et al. Mutations in C12orf65 in patients with encephalomyopathy and a mitochondrial translation defect.

PMID: 20186120 by Richter R., et al. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.