C1QC Antibodies

AND C1QC ELISA kits, C1QC Proteins

Many biological assays use antibodies to detect C1QC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C1QC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C1QC antibodies...

We validate the specificity of these antibodies to C1QC by testing them on tissues known to express C1QC positively and negatively. Browse below to find the C1QC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for C1QC? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the C1QC Western Blot Guide

Designing an IHC experiment for C1QC? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the C1QC IHC Guide

C1QC Infographic by Boster Bio

All C1QC Products

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Product

Figures

Specificity

Applications

Price

Anti-C1QC/Complement Component C1Qc Antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using C1QC Antibody

Western blot analysis of lysates from rat lung, using C1QC Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A05666-1
100ul

C1QC (NM_001114101) Human Over-expression Lysate

C1QC Human Over-expression Lysates NM_001114101

Human

$628
Cat # LS000714
20 µg, 100 µg

C1QC Overview

Facts about Complement C1q subcomponent subunit C.

C1QC 3D structure. Source: alphafold

Complement C1q subcomponent subunit C (C1QC)

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Gene Information

Human
Gene Name:	C1QC
Uniprot:	P02747
Entrez:	714

Family

Belongs to:

No superfamily

Alternative Names

C1qC; C1Q-C; C1QGcomplement component 1, q subcomponent, gamma polypeptide; complement C1q subcomponent subunit C; complement component 1, q subcomponent, C chain; Complement Component C1qC; FLJ27103

Molecular Weight

Mass (kDA):
25.774 kDA

Genomic Context


Human

Location:	1p36.12
Sequence:	1; NC_000001.11 (22643633..22648108)

Subcellular Localizations

Secreted.

Diseases

Lupus Erythematosus, Systemic
Nephritis
Lupus Nephritis
Nerve Damage
Polyneuropathy
Peripheral Nerve Injuries
Autoimmune Diseases
Adenomatous Polyposis Coli
Autoimmune Reaction

Amyloid Neuropathies, Familial
Nervousness
Dysequilibrium Syndrome

Interacting Proteins

C1QBP

Pathways

Fatty Acid Homeostasis
Complement Activation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C1QC

References

PMID: 1706597 by Sellar G.C., et al. Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q.

PMID: 486087 by Reid K.B.M.; Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement.