C6 Infographic
Complement component C6 Info At a glance, species: Human
Popular Antibodies & ELISA Kits
Complement component C6 (C6)
Constituent of the membrane attack complex (MAC) which plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | C6 |
| Uniprot: | P13671 |
| Entrez: | 729 |
Family
| Belongs to: |
|---|
| complement C6/C7/C8/C9 family |
Alternative Names
complement component 6; complement component C6
Molecular Weight
Mass (kDA):
104.786 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.1 |
| Sequence: | 5; NC_000005.10 (41142116..41261486, complement) |
Subcellular Localizations
Secreted.
Diseases
- Glioma
- Neoplasms
- Brain Neoplasms
- Malignant Neoplasms
- Malignant Paraganglionic Neoplasm
- Glioblastoma
- Pain
- Nervousness
- Spinal Cord Injuries
- Astrocytoma
- Dengue Fever
- Malignant Glioma
Interacting Proteins
- NCK1
Pathways
- Transport
- Cell Death
- Cell Proliferation
- Cell Growth
- Localization
- Cell Cycle
- Secretion
- Angiogenesis
- Pathogenesis
- Complement Activation
- Translation
- Cell Differentiation
- Regeneration
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Glycosylation
- Carboxylation
- Hydroxylation
- Methylation
- Acetylation
- Biotinylation
Research Areas
- Immunology
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C6
bosterbio.com/bosterbio-gene-info-cards/C6
References
PMID: 2808363 by Haefliger J.-A., et al. Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
PMID: 2789218 by Discipio R.G., et al. The molecular architecture of human complement component C6.
Featured Complement component C6 Antibodies, ELISA Kits & Proteins
Bosterbio provides high quality Complement component C6 Antibodies & ELISA kits
Anti-Complement component C6 C6 Antibody
SKU: A00317
Reactivity: Human, Rat
Applications: WB
Anti-Complement component C6 C6 Antibody
SKU: A00317-1
Reactivity: Human, Rat
Applications: ELISA, IHC, WB
![Anti-Complement Component 6 (C6) Mouse Monoclonal Antibody [Clone ID: OTI1E2] (M00317)](https://www.bosterbio.com/media/catalog/product/m/0/m00317-anti-complement-component-6-c6-mouse-monoclonal-antibody-clone-id-oti1e2-wb-testing-2.jpg)
Anti-Complement Component 6 (C6) Mouse Monoclonal Antibody [Clone ID: OTI1E2]
SKU: M00317
Reactivity: Human
Applications: WB