Complement component C6 Antibodies

AND C6 ELISA kits, Complement component C6 Proteins

Many biological assays use antibodies to detect Complement component C6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement component C6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement component C6 antibodies...

We validate the specificity of these antibodies to Complement component C6 by testing them on tissues known to express C6 positively and negatively. Browse below to find the C6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C6 Infographic by Boster Bio

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Anti-Complement component C6 C6 Antibody

7 Q&As

Immunohistochemistryt analysis of paraffin-embedded human heart, using C6 Antibody

Western Blot analysis of various cells using C6 Polyclonal Antibody diluted at 1:1000

Human, Rat

ELISA, IF, IHC, WB

$399
Cat # A00317
100μl

Complement Component 6 (C6) (NM_000065) Human Over-expression Lysate

Complement Component 6 (C6) Human Over-expression Lysates NM_000065

Human

$628
Cat # LS000729
20 µg, 100 µg

Anti-C6 Antibody

Human, Mouse

ELISA, IP, IHC, WB

$370
Cat # A00317-2
100 μl/vial

C6 Overview

Facts about Complement component C6.

C6 3D structure. Source: alphafold

Complement component C6 (C6)

Constituent of the membrane attack complex (MAC) which plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. .

Gene Information

Human
Gene Name:	C6
Uniprot:	P13671
Entrez:	729

Family

Belongs to:

complement C6/C7/C8/C9 family

Alternative Names

complement component 6; complement component C6

Molecular Weight

Mass (kDA):
104.786 kDA

Genomic Context


Human

Location:	5p13.1
Sequence:	5; NC_000005.10 (41142116..41261486, complement)

Subcellular Localizations

Secreted.

Diseases

Glioma
Neoplasms
Brain Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Glioblastoma
Pain
Nervousness
Spinal Cord Injuries
Astrocytoma
Dengue Fever
Malignant Glioma

Quadriplegia
Neuroblastoma
Edema
Flexed Fetal Attitude
Compression Of Spinal Cord
Spinal Cord Diseases
Tissue Adhesions

Interacting Proteins

NCK1

Pathways

Transport
Cell Death
Cell Proliferation
Cell Growth
Localization
Cell Cycle
Secretion
Angiogenesis
Pathogenesis
Complement Activation
Translation
Cell Differentiation
Regeneration

Cell Adhesion
Glycosylation
Immune Response
Endocytosis
Glycolysis
Innervation
Cell Migration

PTMs

Phosphorylation
Cleavage
Oxidation
Reduction
Glycosylation
Carboxylation
Hydroxylation
Methylation
Acetylation
Biotinylation

Acylation
Dephosphorylation
Decarboxylation
Ribosylation
Nitration
Myristoylation
Deamination
Ubiquitination
Demethylation
Phosphorothioation

Research Areas

Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C6

References

PMID: 2808363 by Haefliger J.-A., et al. Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.

PMID: 2789218 by Discipio R.G., et al. The molecular architecture of human complement component C6.