Calcium-binding protein 1 (CABP1)

Modulates calcium-dependent action of inositol 1,4,5- triphosphate receptors (ITPRs)(PubMed:14570872). Inhibits agonist- induced intracellular calcium signaling (PubMed:15980432).

Enhances inactivation and doesn't support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin from the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941).